Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Can elderly patients with severe mitral regurgitation be ideal candidates for MitraClip?
Session:
Sessão de Posters 54 - Intervenção valvular mitral
Speaker:
Ana Rita Teixeira
Congress:
CPC 2024
Topic:
H. Interventional Cardiology and Cardiovascular Surgery
Theme:
25. Interventional Cardiology
Subtheme:
25.3 Non-coronary Cardiac Intervention
Session Type:
Cartazes
FP Number:
---
Authors:
Ana Rita Teixeira; André Paulo Ferreira; João Ferreira Reis; Francisco Barbas de Albuquerque; Vera Vaz Ferreira; Luísa Moura Branco; Pedro Rio; Ana Galrinho; António Fiarresga; Duarte Cacela; Rui Cruz Ferreira
Abstract
<p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:11.0pt">Background:</span></strong><span style="font-size:11.0pt"> The MitraClip® system is a well-established percutaneous mitral valve intervention for patients (pts) with severe mitral regurgitation (MR) non-eligible for surgery. However, limited data exist on its efficacy in elderly pts. This study aims to elucidate the procedural safety and 1-year clinical, echocardiographic, and cardiopulmonary exercise testing (CEPT) outcomes in septuagenarians or older.</span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:11.0pt"><span style="color:black">Methods:</span></span></strong><span style="font-size:11.0pt"><span style="color:black"> A retrospective single-center analysis included all patients who underwent MitraClip® implantation for severe and symptomatic MR. Clinical, echocardiographic, and CEPT variables were evaluated at baseline and 12 months post-procedure. Data were analyzed using chi-square for categorical and independent t-tests for continuous variables. Paired-samples t-test compared dependent variable means pre/post MitraClip®, with significance set at p<0.05.</span></span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:11.0pt">Results:</span></strong><span style="font-size:11.0pt"> Of 65 pts, 33 were ≥ 70 years, with a mean age of 79±5 years and a mean left ventricle ejection fraction (LVEF) of 44±12%. NYHA class ≥3 was present in 18 pts. MR grade IV was observed in 66.7%, with 54.5% having a non-ischemic etiology. COAPT inclusion criteria were met in 11 pts. Table 1 presents baseline and echocardiographic characteristics. The elderly cohort had a higher prevalence of atrial fibrillation and a higher STS mortality risk score, but lower tobacco abuse. Younger pts had a more dilated left ventricle and lower LVEF. Successful implantation was achieved in 97% of elderly pts, with 23 presenting mild MR post-procedure. No procedure-related deaths occurred, but 3 immediate complications were noted: 2 chordae ruptures and 1 mitral leaflet perforation. The 1-year survival rate was 79.3%, with 4 pts experiencing at least one heart failure hospitalization (table 1). MitraClip® significantly improved NYHA functional class (<em>p</em>=0.01). <span style="background-color:white"><span style="color:black">The reduction in MR severity achieved after the procedure was sustained at 1-year. </span></span>Significant improvements were seen in both mitral gradient (<em>p</em>=0.045) and regurgitant volume (<em>p</em><0.001). No significant changes in LV systolic function (<em>p</em>=0.324) or volumes were noted in the elderly group, nor in TAPSE and sPAP. No significant CPET parameter changes were reported.</span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:11.0pt">Conclusion</span></strong><span style="font-size:11.0pt">: In our population, MitraClip® proved safe and effective in elderly patients with severe MR and high surgical risk. Results suggest that advanced age alone should not limit MitraClip® edge-to-edge repair in well-selected patients.</span></span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site