Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Aortic Valve Calcification as a Surrogate Parameter for Paravalvular Regurgitation Following Transcatheter Aortic Valve Implantation
Session:
Sessão de Posters 53 - Complicações de TAVI
Speaker:
Fabiana Duarte
Congress:
CPC 2024
Topic:
H. Interventional Cardiology and Cardiovascular Surgery
Theme:
25. Interventional Cardiology
Subtheme:
25.3 Non-coronary Cardiac Intervention
Session Type:
Cartazes
FP Number:
---
Authors:
Fabiana Silva Duarte; Rafael Silva-Teixeira; Fábio Nunes; Inês Neves; Marta Leite; André Lobo; Marta Almeida; Pedro Braga; Nuno Dias Ferreira; Ricardo Fontes-Carvalho
Abstract
<p>Introduction: Transcatheter aortic valve replacement (TAVR) is the preferred treatment for elderly patients with severe aortic stenosis, regardless of surgical risk. Recent data have extended its use for younger patients with lower surgical risk. Albeit its demonstrated safety profile, paravalvular aortic regurgitation (AR) complication rates remain relatively high. The amount and spatial distribution of calcium in the aortic valve have been explored as potential predictors of paravalvular AR.</p> <p>Objective: We aimed to evaluate the accuracy of aortic valve calcium score, total aortic valve calcium volume and individual aortic valve leaflet calcium quantification in predicting paravalvular AR complications.</p> <p>Methods: Retrospective single-center analysis included 97 patients who underwent TAVR since January 2018. Aortic valve calcification was measure on non-contrast EKG-gated multi-detector computed tomography (CT). Quantification of individual aortic valve leaflets calcification was performed through short-axis reconstructions. All patients had at least one echocardiography reevaluation in the first month after the procedure.</p> <p>Results: In our cohort, mean age was 76.1±8.2 years and the mean body mass index was 1.8±0.2 kg/m2; 89.6% had hypertension, 82.3% dyslipidemia and 42.7% diabetes. CT scans performed before TAVR revealed a median calcium volume of 1843 mm3 (IQR 170 – 6031) and a median total aortic valve calcium score of 2033 (IQR 170 – 7892).<br /> Twenty-one (21.9%) patients developed post-TAVR paravalvular regurgitation, with 8.3% being moderate-to-severe cases. Aortic valve calcium score (2390 vs 1859, p=0.030) and volume (1859 vs 1490, p=0.016) were higher in patients with any degree of paravalvular AR. However, individual aortic valve leaflet score was not associated with differences in prosthetic regurgitation (p>0.05). In multivariate analysis, no baseline characteristics predicted paravalvular AR.</p> <p>Conclusion: Our study supports that a higher aortic valve calcium score and volume, assessed by CT scan, were associated with higher rates of paravalvular regurgitation following TAVR. However, the same was not verified for individual valve leaflet calcium distribution. Further studies are required to validate additional markers of potential complications following TAVR.</p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site