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Evaluation of Fetal Cardiac Function in Gestational Diabetes Mellitus by Two-Dimensional Speckle-Tracking Technology
Session:
Sessão de Posters 49 - Cardiopatias Congénitas
Speaker:
Maria Ana Estevens
Congress:
CPC 2024
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
20. Congenital Heart Disease and Pediatric Cardiology
Subtheme:
20.6 Congenital Heart Disease – Clinical
Session Type:
Cartazes
FP Number:
---
Authors:
Maria Ana Estevens; Graça Nogueira; Susana Cordeiro; Jorge Lima; Rui Anjos
Abstract
<p>Background: Subclinical fetal cardiac dysfunction is recently described as an effect of gestacional diabetes (GD). Two-dimensional speckle-tracking technology for fetal heart evaluation is currently available. Feasibility, reproducibility and normal range values have already been reported. This study aimed to assess the effect of GD on fetal cardiac function by two-dimensional speckle-tracking technology. </p> <p>Methods: We performed a prospective observational study that included 89 pregnant women, 42 with GD and 47healthy. A four-chamber 3s cine-loop was recorded and analyzed with Fetal Heart Quantification (FetalHQ® from GE®). Global longitudinal strain (GLS) for both ventricles was calculated. Demographic data shows no 3rd trimester scans or uncontroled GD. Demographic and cardiac differences between the two groups were analyzed.</p> <p>Results: Gestacional age (GA) was 23 (SD 3.02) weeks. GLS of left ventricle (LV): –21.88% (SD 5.81%), right ventricle (RV) –17.16% (SD 6.89%), left atrium (LA) 22.32% (SD 8.10%). T test and linear regression analysis show statistic correlation between LV and RV GLS (beta 0.423; p-value 0.0006, Multiple R-squared: 0.13). No significant correlation was found between GD and GLS values nor between gestational age and GLS values.</p> <p>Conclusions: GLS was a feasible and reproductible technique. LV and RV strain have a significant correlationas expected. No significant correlation was found between LV and LA strain. No evidence in this study of cardiac dysfunction in GD patients at 2nd trimester in a well controlled cohort. Larger studies are needed.</p>
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