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Myocardial Bridging in Hypertrophic Cardiomyopathy: Prevalence, Characteristics, and Clinical Implications
Session:
Sessão de Posters 45 - Miocardiopatia hipertrófica
Speaker:
Inês Ferreira Neves
Congress:
CPC 2024
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
17. Myocardial Disease
Subtheme:
17.4 Myocardial Disease – Treatment
Session Type:
Cartazes
FP Number:
---
Authors:
Inês Ferreira Neves; Miguel Marques Antunes; Pedro Garcia Brás; André Paulo Ferreira; Isabel Cardoso; José Viegas; Inês Almeida; Tiago Mendonça; Rúben Ramos; António Fiarresga; Rui Cruz Ferreira; Sílvia Aguiar Rosa
Abstract
<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:10.0pt">Introduction:</span></strong><span style="font-size:10.0pt"> Myocardial bridging has a prevalence ranging from 1% to 3% in the general population, previous studies have shown that it is significantly more prevalent in patients with Hypertrophic Cardiomyopathy (HCM), reaching about 25% in some cohorts. The clinical relevance of myocardial bridging in patients with HCM is still mostly unknown, with some studies suggesting that it has an impact on clinical and imagological outcomes, whilst others suggest that the condition is mostly benign and has no overall outcome impact.</span></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-size:10.0pt">We aimed to study the prevalence, laboratory and imagological characteristics and clinical implications of myocardial bridging in a population of patients with HCM.</span></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:10.0pt">Methods: </span></strong><span style="font-size:10.0pt">Patients with HCM accompanied at our center who had coronary anatomy studied by either cardiac catheterization (CAT) or</span> <span style="font-size:10.0pt">Coronary computed tomography angiography (CCTA) were included. We retrospectively analyzed the prevalence of myocardial bridging in our population and correlated the phenomenon to cardiovascular risk factors (RF), symptoms, and laboratory and cardiac magnetic resonance (CMR) findings.</span></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:10.0pt">Results: </span></strong><span style="font-size:10.0pt">Sixty-four patients with HCM (mean age 66.7±11.6, 50% male sex) were included. Fifteen (23%) patients (age 60.73±8.5, 73.3% male sex) had myocardial bridging. The groups had similar baseline characteristics, and no significant differences were registered when comparing clinical aspects such as angina, classified according to Canadian Cardiovascular Society (CCS) scale, or heart failure symptoms, classified according to New York Heart Association (NYHA) class. No significant differences were seen regarding the contemplated laboratory values. Regarding the CMR findings, there were no differences in the occurrence of perfusion defects or in late gadolinium enhancement (LGE), considering the number of segments and the percentage of the left ventricle affected.</span></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:10.0pt">Conclusion:</span></strong><span style="font-size:10.0pt"> Our cohort of HCM patients had a prevalence of myocardial bridging similar to that described in previous studies. This condition seems to have no overall impact in the clinical presentation, ischemia and myocardial fibrosis.</span></span></span></p>
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