Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
ASSESSMENT OF SUBCLINICAL HYPERVOLEMIA BY BIOIMPEDANCE SPECTROSCOPY IN HEART FAILURE
Session:
Sessão de Posters 38 - Insuficiência cardíaca avançada
Speaker:
Bruno Bragança
Congress:
CPC 2024
Topic:
D. Heart Failure
Theme:
10. Chronic Heart Failure
Subtheme:
10.6 Chronic Heart Failure - Clinical
Session Type:
Cartazes
FP Number:
---
Authors:
Bruno Bragança; Mauro Moreira; Rafaela G. Lopes; Inês G. Campos; Ricardo Barbosa; Sónia Apolinário; Patrícia Silva; Licínia Aguiar; Magda Silva; Aurora Andrade
Abstract
<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-family:"Arial",sans-serif">Background:</span></strong><span style="font-family:"Arial",sans-serif"> Expansion and redistribution of extracellular fluid (ECF) precedes heart failure (HF) decompensation. Subclinical hypervolemia has a dismal impact on the prognosis of HF patients<sup>1</sup>. Bioimpedance spectroscopy (BIS) technology is able to estimate ECF expansion in hypervolemia states non-invasively. However, it remains to be explored whether BIS improves the detection of subclinical hypervolemia in HF. </span></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-family:"Arial",sans-serif">Methods: </span></strong><span style="font-family:"Arial",sans-serif">Fifty-six adult outpatients under guideline-directed medical therapy for HF with reduced ejection fraction (HFrEF) were recruited for a single-center prospective study. BIS (InBody BWA 2.0) was calibrated to detect hypervolemia using healthy control subjects and clinical congestive HF patients. Subclinical hypervolemia was defined as a raised ECF adjusted to total body water (ECF/TBW above 1<sup>st</sup> quartile) despite the absence of clinical signs of hypervolemia according to the EVEREST score<sup>2</sup>. Clinical evaluation was blinded for BIS data. Data is presented as mean±sd.</span></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-family:"Arial",sans-serif">Results: </span></strong><span style="font-family:"Arial",sans-serif">In this cohort, 68% were male, mean age 65±11 years, body mass index (26.9±14Kg/m<sup>2</sup>), left ventricular ejection fraction (LVEF) 34±13%, NT-proBNP 3290±5706 pg/mL. Body fluid distribution of HF patients was as follows: total body water (TBW; 38.4±8L); ECF (15.0±3L), ECF/TBW (39±2%). 37 HF patients (66%) showed raised ECF/TBW>38.6% (1<sup>st</sup> quartile) and, among them, 29 (52%) had no clinical signs of hypervolemia identified at physical examination. ECF/TBW positively correlated with NT-proBNP levels (r=0.37; <em>p</em>=0.01), but not with serum albumin, sodium, gamma-glutamyl transferase or alkaline phosphatase (<em>p</em>>0.05). In the subclinical hypervolemia group, NT-proBNP levels were significantly raised but did not differ significantly from the clinical hypervolemia group (4490±6908 pg/mL vs 4316±5029 pg/mL,<em> p</em>>0.05).</span></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-family:"Arial",sans-serif">Conclusions:</span></strong><span style="font-family:"Arial",sans-serif"> Subclinical hypervolemia is prevalent in outpatients with HFrEF. ECF/TBW correlates with routine markers of hypervolemia. BIS has sensitivity to detect subclinical hypervolemia in HF patients.</span></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-size:8.0pt"><span style="font-family:"Arial",sans-serif">1 – WL. Milner, et al. Journal of Cardiac Failure, 2021 | 2 - A. Ambrosy, et al. European Heart Journal, 2013 </span></span></span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site