Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Left main coronary artery angioplasty in patients with non-complex coronary artery disease
Session:
Sessão de Posters 42 - Revascularização de tronco comum
Speaker:
Joana Massa Pereira
Congress:
CPC 2024
Topic:
H. Interventional Cardiology and Cardiovascular Surgery
Theme:
25. Interventional Cardiology
Subtheme:
25.2 Coronary Intervention
Session Type:
Cartazes
FP Number:
---
Authors:
Joana Massa Pereira; Sofia Andraz; Lucas Hamann; Hugo Alex Costa; Miguel Espírito Santo; Daniela Carvalho; Pedro Azevedo; Raquel Fernandes; Dina Bento; João Sousa Bispo; Hugo Vinhas; Jorge Mimoso
Abstract
<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Introduction: </strong>The treatment of choice of left main coronary artery (LMCA) disease has been subject to intense debate and investigation in the last decade. Although it is not the standard of care, angioplasty of LMCA has been increasing mainly in non-complex coronary artery disease (CAD) patients. </span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Objective: </strong>Characterize the population submitted to LMCA angioplasty. Compare cardiovascular (CV) mortality, acute coronary syndromes (ACS) and the need of repeated revascularization (composite primary outcome) regarding the presence of complex CAD, in 2 years follow-up. Try to identify prognostic factors for the primary outcome.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Methods:</strong> Retrospective study between 2019/2020, composed of n=120 patients who were submitted to LMCA angioplasty. Complex CAD was defined as Syntax score > 22. Categorical variables are presented as frequencies and percentages, and continuous variables as means and standard deviations, or medians and interquartile ranges for variables with skewed distribution or a significant Shapiro-Wilk test. Multivariate analysis was performed using logistic regression. P value < 0.05 indicates statistical significance.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Results:</strong> A total of 120 patients were identified, with a mean age of 70.5 ± 10.8 years, 76.7% were male. 75,0% had hypertension, 60.8% dyslipidemia, 34.2% diabetes, 20.2% obesity, 8.3% chronic renal disease and 21.7% were smokers. 72.5% presented with ACS and 55% had left main plus one atherosclerotic coronary artery disease. Overall, after the procedure, the mean absolute increase in LVEF was 6% (p<0.001). Primary outcome (composite) occurred in 21 (18.6%) patients, mainly in complex CAD group (n=9, 45% vs n=12, 12.9%, p<0.001) and driven by CV mortality (n=8, 40% vs n=4, 4.3%, p<0.001) in 2 years follow-up. Syntax score > 22 was an independent predictor of the primary outcome (p=0.015, OR 4.25, 95% CI 1.32 to 13.6), predicting 4 times more events.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Conclusion: </strong>In the sample analyzed, the benefit of LMCA angioplasty in patients with non-complex CAD seems to remain, with low rates of hard CV outcomes and improvement of LVEF in 2 years follow-up. Nevertheless, in complex CAD patients, this revascularization strategy showed worst outcomes with higher CV mortality. In the last group, a surgical approach should be considered, in line with the guidelines.</span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site