Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Prognostic value of programmed electrical stimulation in Brugada Syndrome: a single-center study.
Session:
Sessão de Posters 28 - Morte súbita cardíaca
Speaker:
João Gouveia Fiuza
Congress:
CPC 2024
Topic:
C. Arrhythmias and Device Therapy
Theme:
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
Subtheme:
08.4 Ventricular Arrhythmias and SCD - Treatment
Session Type:
Cartazes
FP Number:
---
Authors:
João Gouveia Fiuza; Vanda Devesa Neto; Júlio Gil Pereira; João Primo; Luís Ferreira Dos Santos; António Costa
Abstract
<p><strong><span style="font-size:12.0pt"><span style="font-family:"Calibri Light",sans-serif">Introduction:</span></span></strong><span style="font-size:12.0pt"><span style="font-family:"Calibri Light",sans-serif"> Prognostic value of programmed electrical stimulation (PES) in Brugada Syndrome (BrS) remains controversial. Implantation of an implantable cardioverter-defibrillator is this population is the only reliable form of sudden cardiac death (SCD) prevention.<br /> <strong>Purpose:</strong> To determine if induction of sustained ventricular arrhythmia (VA) in PES predicts cardiac events (CE), defined as the composite of SCD, ICD shocks, or unexplained syncope.<br /> <strong>Methods:</strong> A retrospective analysis of 34 patients with spontaneous or pharmacologically induced type 1 Brugada pattern, submitted to an electrophysiology study with PES in a 5-year period at a Portuguese Center, was performed. The electrophysiological study (EPS) followed a protocol comprising PES at the right ventricle apex with two pacing cycle lengths (600 and 400ms) and the introduction of up to three ventricular extrastimuli with a minimum coupling interval of 200 ms. A positive test result was defined as the induction of sustained ventricular arrythmia lasting for more than 30 seconds or requiring termination due to hemodynamic compromise. The inducibility at programmed ventricular stimulation was considered a valid indication for the implantation of an ICD. Patients were followed until the end of 2022. Hospital records and monitoring data from cardiac devices were consulted. The Mann-Whitney U test was used for comparison between groups. Binary logistic regression through the stepwise method was performed to evaluate categorical features.<br /> <strong>Results:</strong> 35% (n=12) and 27% (n=9) had spontaneous type 1 and type 2 Brugada patterns in basal electrocardiography, respectively. 23% (n=8) had VA induced by PES. The mean age was 51.2±12.3 years. 71% (n=24) were male. 15% (n=5) had history of cardiac syncope, and 27% (n=9) had a family history of SCD. 9% (n=3) were tested for SNC5A mutation and were positive. Mean AH time and HV time were 105±31.9ms and 49±8.5ms. During the follow-up, 9% (n=3) suffered a CE (2 unexplained syncope and 1 SCD). None of the patients who suffered CE had VA inducible in PES study. There was no statistical significance in the occurrence of cardiac events when comparing both groups (VA induced in PES vs. no induced arrhythmia) (p=0.49, OR 0.89, IC 95% 0.70;1.02). Through binary logistics, adjusted for potential confounders (gender, history of syncope, history of family SCD and identification of a genetic variant), patients with spontaneous type 1 Brugada pattern in basal electrocardiography were 2.2 times more likely to have a CE (IC 95% 0.12;40.2).<br /> <strong>Conclusion: </strong>In this population, VA induced by PES was not a predictor of CE during the follow-up period, highlighting the difficulty of risk stratification in patients with BrS. New risk-stratification tools are urgently needed to select those patients at higher risk of SCD, who are candidates for prophylactic ICD implantation.</span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site