Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Long-term exercise tolerance and quality of life after Balloon Pulmonary Angioplasty (BPA): is there a role for right heart catheterization?
Session:
Comunicações Orais - Sessão 12 - Hipertensão Pulmonar
Speaker:
Mariana Martinho
Congress:
CPC 2024
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
Subtheme:
21.4 Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure - Treatment
Session Type:
Comunicações Orais
FP Number:
---
Authors:
Mariana Martinho; Rita Calé; Filipa Ferreira; Sofia Alegria; Débora Repolho; Bárbara Marques Ferreira; João Mirinha Luz; Sílvia Vitorino; Pedro Santos; Hélder Pereira
Abstract
<p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:10.5pt">Introduction</span></strong><span style="font-size:10.5pt">: Resting pulmonary haemodynamics and exercise capacity are good parameters of Balloon Pulmonary Angioplasty (BPA) effectiveness in Chronic Thromboembolic Pulmonary Hypertension (CTEPH) treatment. Increasing evidence regarding resting parameters suggest sustained long-term benefits of BPA. Exercise right heart catheterization (eRHC) might provide additional information on those outcomes.</span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:10.5pt">Purpose</span></strong><span style="font-size:10.5pt">: To assess the long-term clinical and haemodynamic effectiveness of BPA, at rest and with exercise, in a Portuguese PH-referral center, and correlate it with the impact in regular daily activities. </span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:10.5pt">Methods</span></strong><span style="font-size:10.5pt">: Prospective series of consecutive pts with inoperable or residual CTEPH after surgery, who completed a minimum of 3y follow-up (FUP) after a total of 63 BPA sessions, between 2017 and 2020. Clinical, imaging and haemodynamic data were collected and quality of life (QoL) assessed by the self-reported short form of health-related quality of life scale (SF-36). Long-term rest haemodynamics and eRHC mPAP/CO slope were correlated with clinical parameters of exercise capacity and QoL. </span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:10.5pt"><span style="color:black">Results:</span></span></strong><span style="font-size:10.5pt"><span style="color:black"> Of 12pts, mean age was 64±12y and 66.7% were females. At baseline, 83.3% of pts were treated with pulmonary vasodilators (3pts with i.v. prostacyclin analogs) and 3pts required long-term oxygen therapy. There was a mean of 5.3±1.9 sessions/pt, a mean of 9.8±2.4 targeted segments/session; 1pt died of cancer during FUP and 2pts interrupted the program prematurely. The 9pts that completed 3y-FUP had i.v. vasodilators and oxygen therapy withdrawn, with significant improvement in median WHO functional class (2.0 vs 1.0, p=0.015) and with a reported mean SF-36 physical capacity of 76%. Right ventricle fractional area change improved form 31.1±12.2 to 42.1±5.1% (p=0.047), resting mPAP reduced from 37.3±13.3 to 29.8±9.7mmHg (p=0.166) and PVR from 6.2±3.0 to 3.6±1.4WU (p=0.066). Resting haemodynamic parametes did not correlate significantly with clinical parameters of exercise capacity. At a mean 43±8months after the last BPA session, eRHC was performed in 6pts and showed a mean mPAP/CO slope of 7.4±6.0mmHg/L/min (83.3% with exercise pulmonary hypertension). This slope showed correlation with NT-proBNP and several clinical parameters of physical capacity (table). No complications were reported in eRHC. </span></span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:10.5pt"><span style="color:black">Conclusions</span></span></strong><span style="font-size:10.5pt"><span style="color:black">: Significant improvements in functional capacity, resting imaging and resting haemodynamic parameters were observed at long-term FUP after BPA. However, a majority of pts maintain worsening of PH with exercise and eRHC appears to confer an added value in assessing clinical outcomes.</span></span></span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site