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Calcium Score a predictor of heart failure improvement after Transcatheter Aortic Valvular Implantation
Session:
Posters (Sessão 6 - Écran 8) - Tomografia Computorizada Cardíaca
Speaker:
Francisco Homem de Gouveia e Sousa
Congress:
CPC 2023
Topic:
B. Imaging
Theme:
03. Imaging
Subtheme:
03.2 Computed Tomography
Session Type:
Pósters Electrónicos
FP Number:
---
Authors:
Francisco Sousa; Débora Sá; Marina Santos; Margarida Temtem; Ricardo Rodrigues; Bruno Silva; Graça Caires; Diogo Rijo; Marco Gomes Serrão; João Adriano Sousa; João Manuel Rodrigues; António Drumond Freitas
Abstract
<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Background: Aortic valve calcium score (AVCS) measures calcium deposition on the aortic valve. It is a complementary exam to access aortic stenosis, being echocardiography the gold standard. Severe aortic stenosis is considered when aortic calcium is >2000 AU. Greater levels of aortic valve calcification will make heart failure more likely. </span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Methods: Cardiac angio CT is performed routinely in all 52 patients before Transcatheter Aortic Valvular Implantation (TAVI). NTproBNP determination was measured before TAVI and three months after. The relative reduction of NTProBNP was calculated and used as the primary endpoint. AVCS values were divided into 2 groups: (A) AVCS ≤ 2000 (n=13; 25%), (B) AVCS >2000 (n=39; 75%). Groups were tested regarding the degree of NTproBNP reduction using the Mann-Whitney test and later tested for reductions >50% using chi-square test.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Results: </span></span><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Mean age in each group was (A=82,9±3,6; B=80,2±6,62) years. Mean AVCS was A=4287(±1908) B=3257,9 (±1939) (p=0,03). NTproBNP reduction was significantly higher among patients with higher AVCS (A=26.9% ± 28; B=50.0% ± 33.22, p=0.02). Reductions above 50% were consistently higher in group B (A=21.4%; B=53.8%, p=0.01).</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Conclusion: </span></span><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Increased calcification of the aortic valve is associated with greater NT Pro BNP reduction. TAVI has a larger impact on Heart failure improvement in patients with a more severe and prolonged aortic stenosis. AVCS is a useful complementary tool to echocardiography in moderate to severe aortic stenosis, as lower AVCS are associated with more modest NTproBNP reductions after TAVI. </span></span></p>
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