Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
The KAsH ONE trial - Early discharge in myocardial infarction: preliminary results
Session:
Posters (Sessão 6 - Écran 7) - Enfarte miocárdio elevação ST
Speaker:
Rafaela G. Lopes
Congress:
CPC 2023
Topic:
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
Theme:
13. Acute Coronary Syndromes
Subtheme:
13.7 Acute Coronary Syndromes - Other
Session Type:
Pósters Electrónicos
FP Number:
---
Authors:
Rafaela G. Lopes; Débora Sá; Isabel Cruz; Bruno Bragança; Inês Gomes Campos; Mauro Moreira; Glória Abreu; António Drumond; Joel Ponte Monteiro
Abstract
<p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong>Introduction: </strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif">The KAsH score is a simple clinical score for acute coronary syndromes used at first medical contact. It has excellent predictive power for in-hospital mortality, specifically isolating patients with very low mortality risk during admission. The aim of this study is to evaluate the</span></span><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif">mortality outcomes of patients admitted due to myocardial infarction (MI) that remain in KAsH score of 1 during the first 48 hours of hospitalization. </span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong>Methods: </strong></span></span></p> <p style="text-align:justify"><span style="font-size:12.0pt"><span style="font-family:"Calibri",sans-serif">Multicentric study of consecutive patients admitted with myocardial infarction in two tertiary centers. <span style="color:#212121">Patients’ demographic, clinical management and clinical outcome data were collected. KAsH was calculated using the formula: Killip-Kimball: x Age x Heart Rate / Systolic blood pressure, and categorized using the recomemended cut-offs: <40; 40-90; 90-190; > 190 . Patients were divided in two groups: A) patients with KAsH score of 1 at admission, 24 and 48 hours (KAsH-1) vs B) patients with higher scores of KAsH (Non KAsH-1). The primary endpoint was all-cause mortality during the index hospitalization. Secondary endpoint was mortality at 30 days of follow up.</span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong>Results: </strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif">A total of 196 patients were included, with mean age of 66.8±12.6 years, 74% were male and 43.4% had ST-elevation myocardial infarction. Regarding background comorbidities, 28.1% had diabetes, 70.4% hypertension, 64.8% dyslipidemia and 9.4% heart failure. KAsH-1 group corresponded to 27.7% (n=54) of patients. There were no differences between Non KAsH1 and KasH1 groups regarding diagnosis of STEMI (41,1% vs 48.1% p=0.783), history of coronary artery disease (22.7% vs 25.6%, p= 0.718), diabetes (35.7 vs 25.9%, p = 0.199) or hypertension (71.3% vs 61.1%, p= 0.071). The male gender was more frequent in the KAsH 1 group (68.1% vs 90.7 %, p= 0.01.</span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif">KAsH displayed excellent predictive capacity to predict in-hospital mortality (AUC 0.905 at admission).</span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif">During the index hospitalization 11 deaths occurred (mortality of 6.1%). No deaths occurred in the KAsH-1 group (mortality =0%). At 30 days after discharge there were 12 deaths in the non KAsH-1 group (mortality of 8.5%). There were no registered deaths in the KAsH-1 group.</span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong>Conclusion: </strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif">This multicentric work shows that a low sequential KAsH evaluation is highly effective at selecting patients without in-hospital and short-term mortality. This work is the basis for a prospective, randomized trial to test KAsH to identify patients for an early discharge.</span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site