SPC365

Validation of an Aerobic Fitness Questionnaire in a cohort of Portuguese adult cardiac patients

Session: Posters (Sessão 6 - Écran 4) - Provas de Esforço e Reabilitação
Speaker: Maria Rita Giestas Lima

Congress: CPC 2023
Topic: J. Preventive Cardiology
Theme: 29. Rehabilitation and Sports Cardiology
Subtheme: 29.2 Cardiovascular Rehabilitation
Session Type: Pósters Electrónicos
FP Number: ---
Authors: Maria Rita Giestas Lima; João Presume; Gonçalo Cunha; Rita Amador; Luís Moreno; Anaí Durazzo; Claudio Gil Araújo; Miguel Mendes

<p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-family:&quot;Times New Roman&quot;,serif">[Introduction] </span></span></span></p>

<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-family:&quot;Times New Roman&quot;,serif">Cardiopulmonary exercise testing (CPET) is the gold-standard to quantify functional capacity in patients with cardiac disease. However, it is costly and not widely available. CLINIMEX aerobic fitness questionnaire (C-AFQ), previously published in 2019, is a non-invasive tool validated for Brazilian adults that, based on patient responses for a list of activities with known energy requirements, predicts the aerobic fitness in metabolic equivalents, from which maximum oxygen consumption (VO2) may be derived. C-AFQ was designed to overcome the unavailability of CPET in many centres, yet its validity in Portuguese cardiac patients remains unknown. </span></span></span></p>

<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-family:&quot;Times New Roman&quot;,serif">[Aim] </span></span></span></p>

<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-family:&quot;Times New Roman&quot;,serif">To evaluate the performance of the C-AFQ in predicting VO2 measured by a CPET in a Portuguese cohort of adult patients with cardiac disease. </span></span></span></p>

<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-family:&quot;Times New Roman&quot;,serif">[Methods] </span></span></span></p>

<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-family:&quot;Times New Roman&quot;,serif">We performed a single-centre prospective study enrolling consecutive patients who underwent CPET from April to November 2022. The main indications for CPET were assessment for cardiac rehabilitation admission or functional capacity for cardiovascular risk stratification. Pearson&acute;s correlation coefficient was used to assess the correlation between VO2 predicted by the questionnaire and the VO2 measured by CPET.</span></span></span></p>

<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-family:&quot;Times New Roman&quot;,serif">[Results] </span></span></span></p>

<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-family:&quot;Times New Roman&quot;,serif">A total of 171 patients were included with a mean age 63&plusmn;12 years, 68% male, 36% were included in the early phase post-myocardial infarction and 64% had chronic heart failure. Mean left ventricle ejection fraction [LVEF] was 47&plusmn;12%. A significant correlation was found between VO2 measured by CPET and the VO2 predicted by C-AFQ (r=0.741, p&lt;0.001). A slightly better performance of the C-AFQ was observed in male patients younger than 70 years compared with female and older patients (r=0.711, p&lt;0.001). We also found a moderate correlation in the subgroup of post-acute myocardial infarction (r=0.727, p&lt;0.001), and a strong correlation in patients with heart failure (r=0.771, p&lt;0.001), including those with </span><span style="font-family:&quot;Times New Roman&quot;,serif">LVEF&le;40% (N=52; 30.4%) </span><span style="font-family:&quot;Times New Roman&quot;,serif">(r=0.723, p&lt;0.001). The results were similar independently of respiratory exchange ratio.</span></span></span></p>

<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-family:&quot;Times New Roman&quot;,serif">[Conclusion]</span></span></span></p>

<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="font-family:&quot;Times New Roman&quot;,serif">C-AFQ significantly estimated the aerobic fitness in this cohort of patients, remaining significant across all subgroups. In summary, C-AFQ may be useful in the assessment of functional capacity of Portuguese cardiac patients when a CPET is not readily available.</span></span></span></p>