Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Can gender play a role in Myocardial Infarction with No Obstructive Coronary Atherosclerosis?
Session:
Posters (Sessão 6 - Écran 3) - MINOCA
Speaker:
André Cabrita
Congress:
CPC 2023
Topic:
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
Theme:
13. Acute Coronary Syndromes
Subtheme:
13.7 Acute Coronary Syndromes - Other
Session Type:
Pósters Electrónicos
FP Number:
---
Authors:
André Cabrita; Catarina Marques; Miguel Carvalho; Mariana Vasconcelos; Filipe Macedo
Abstract
<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Background:</strong> Myocardial Infarction with No Obstructive Coronary Atherosclerosis (MINOCA) is typical of younger patients, mostly women, with less cardiovascular risk factors (CVRF).</span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Purpose: </strong>To determine whether gender implies differences in the presentation, cardiac examinations or treatment of patients with MINOCA.</span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Methods:</strong> We developed a prospective 6-year study, consisting of consultation of medical records of all patients admitted in the Cardiology Department of our institution due to a diagnosis of MINOCA. We divided the patients by gender for comparison: men vs women. </span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Results: </strong>Our cohort consisted of 76 patients admitted with a diagnosis of MINOCA, mostly men (65,8%). Women were older (67 ± 5 vs 48 ± 5 years-old) and revealed a higher burden of CVRF, such as hypertension (42,3 vs 34%), type 2- diabetes <em>mellitus</em> (19,2 vs 2%), dyslipidemia (38,5 vs 24%) and obesity (34,6 vs 16%). Women showed most often absence of ECG abnormalities (38,5 vs 28%) and men had a higher prevalence (28 vs 3,8%) of ST-segment elevation mimicking ST-elevation myocardial infarction (STEMI). Surprisingly, women denoted more segmental wall-motion segmental abnormalities (57,7 vs 36%) on echocardiogram. Evaluating cardiac enzymes, men showed higher elevation of high-sensitivity troponin I (8490 ± 6691 vs 4187 ± 3093 ng/L) and women a higher value of B-type natriuretic peptide (BNP) (653 ± 212 vs 161 ± 59 pg/mL). Women had fewer abnormalities on CMR, so it was considered normal more often (34,6 vs 18%) and denoted higher left-ventricle ejection fraction (59 ± 7 vs 53 ± 5%). Men were associated with late gadolinium enhancement (LGE) (64 vs 34,6%; p=0.004) and myocardial edema (48 vs 23,1%; p=0.0017) on CMR. On CMR analysis, men presented more often with a global pattern of abnormalities (32 vs 11,5%) and a non-ischemic pattern (38 vs 23,1%). Accordingly, men were associated with a higher probability of establishing the cause of MINOCA by CMR (86% vs 69,2%; p=0.028). </span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Conclusion: </strong>In our cohort, although women were older, had a higher burden of CVRF, ECG and echocardiogram alterations, they revealed less abnormalities on CMR. Men were associated with LGE and myocardial edema on CMR, and revealed a higher probability of establishing the cause of MINOCA. This study raises the question on gender differences in MINOCA patients and the need for more studies on this subject.</span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site