Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Another way to study risk factors for aortic valve calcification
Session:
Posters (Sessão 2 - Écran 4) - Doença valvular
Speaker:
Diana Vale Carvalho
Congress:
CPC 2023
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
15. Valvular Heart Disease
Subtheme:
15.7 Valvular Heart Disease - Other
Session Type:
Pósters Electrónicos
FP Number:
---
Authors:
Diana Vale Carvalho; Rita Veiga; Margarida Cabral; Raquel Ferreira; Mesquita Bastos; Rita Faria; Nuno Ferreira
Abstract
<p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif">Background</span></span></strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif">Aortic stenosis is the most prevalent valvular pathology and the degenerative etiology is the most common in developed countries. Some evidence suggests that atherosclerosis risk factors may also be involved in the development of aortic stenosis.</span></span></span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif">Purpose </span></span></strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif">This study aims to clarify which cardiovascular risk factors best correlate with aortic valve calcification, using a method of quantification of valve calcium volume.</span></span></span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif">Methods</span></span></strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><span style="font-size:11.0pt">A retrospective study included patients who submitted cardiac surgery and underwent prior concontrast computed tomography (CT). Aortic valve calcification volume (AVCV) was quantified using a volume-rendering method.</span></span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:11.0pt">Results</span></strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><span style="font-size:11.0pt">148 patients were included (mean age=70,5±4,9y; 60,8% men). Most patients underwent aortic valve replacement surgery (66.9%). The mean value of the aortic valve calcification volume was 1,640</span><span style="font-size:11.0pt"><span style="font-family:Symbol">±</span></span><span style="font-size:11.0pt">1,030cm3. The mean value of the mean gradient in the aortic valve assessed by echocardiography was 50,79±15,37 mmHg). Dyslipidemia and arterial hypertension were the most prevalent risk factors (77% and 75%, respectively). Most cardiovascular risk factors were associated with higher AVCV, except for diabetes and smoking history. Regarding the history of cardiovascular disease, it was observed that only patients with a history of coronary artery disease had higher volumes of calcium in the aortic valve. The univariate analysis found that dyslipidemia was the only risk factor/comorbidity that was significantly associated with higher AVCV (1,154±1,456 vs 1,802 ± 1,523 p=0,025). Considering the volume of calcium as a method of assessing the severity of aortic stenosis, it was observed that there is a positive, moderate and statistically significant correlation between AVCV and the mean gradient in the aortic valve (</span><em><span style="font-size:11.0pt"><span style="font-family:"Cambria Math",serif"><span style="color:black">ρ</span></span></span></em><span style="font-size:11.0pt"> =0.5; p<0.001).</span></span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><strong><span style="font-size:11.0pt">Conclusions</span></strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><span style="font-size:11.0pt">Cardiovascular risk factors are also associated with the development of degenerative aortic stenosis, which may have therapeutic implications in the future. Dyslipidemia appears to be a determining risk factor in the development of aortic valve calcification.</span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><span style="font-size:11.0pt">Sometimes it is sometimes difficult to assess the severity of aortic stenosis, therefore the determination of the AVCV may be an alternative method for diagnosis. </span></span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site