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Comparison of 5 Acute Pulmonary Embolism Mortality Risk Scores in Patients with COVID-19
Session:
Posters (Sessão 6 - Écran 6) - Doença Cardiovascular em Populações Especiais 2 - Covid 19
Speaker:
Tiago Graça Rodrigues
Congress:
CPC 2022
Topic:
K. Cardiovascular Disease In Special Populations
Theme:
30. Cardiovascular Disease in Special Populations
Subtheme:
30.14 Cardiovascular Disease in Special Populations - Other
Session Type:
Pósters Electrónicos
FP Number:
---
Authors:
Tiago Graça Rodrigues; Beatriz Valente Silva; Rui Placido; Carlos Mendonça; Luisa Urbano; Joana Rigueira; Ana g. Almeida; Fausto j. Pinto
Abstract
<p style="text-align:justify"><span style="font-size:medium"><span style="font-family:Calibri,sans-serif"><span style="color:#000000"><strong><span style="color:black">Objective: </span></strong><span style="color:black">Pulmonary embolism (PE) is a common complication of SARS-CoV-2 infection. We aimed to </span><span style="color:black">explore the short-term outcomes among patients with acute PE and COVID-19 and to further determine and compare the performance of the different prognostic scores (PESI, sPESI, BOVA, FAST and ESC scores) for risk-stratification in this scenario.</span></span></span></span></p> <p style="text-align:justify"><span style="font-size:medium"><span style="font-family:Calibri,sans-serif"><span style="color:#000000"><strong><span style="color:black">Methods: </span></strong><span style="color:black">Retrospective single-centre study of 85 patients with SARS-CoV-2 infection and PE admitted to the Emergency Department (ED). The diagnostic accuracy of each above-mentioned prognostic score was calculated post hoc, and their discriminative power was evaluated through an AUC curve. </span></span></span></span></p> <p style="text-align:justify"><span style="font-size:medium"><span style="font-family:Calibri,sans-serif"><span style="color:#000000"><strong><span style="color:black">Results: </span></strong><span style="color:black">Among the 85 patients, all-cause death occurred within 7 days for 6 patients (7.1%) and within 30 days for 14 patients (16.5%). Despite being older and having a higher percentage of altered mental status on presentation, non-survivors patients did not differ from survivors regarding comorbidities, traditional risk factors for venous thromboembolism and signs and symptoms at the ED presentation.</span></span></span></span></p> <p style="text-align:justify"><span style="font-size:medium"><span style="font-family:Calibri,sans-serif"><span style="color:#000000"> <span style="color:black">Each risk stratification tool had modest discriminative power for 7-day mortality (AUC range, 0.601-0.730) with slightly lower discrimination for 30-day mortality (AUC range, 0.543-0.638) - figure 1. The pair-wise comparison of ROC curves showed that PESI had better predictive value for short-term mortality than ESC score (z test = 3.92, p=0.001) and sPESI (z test =2.43, p=0.015); there is no significant difference between PESI and BOVA score (z test = 1.05, p=0.295) and FAST score (z test = 0.986, p=0.324). </span></span></span></span></p> <p style="text-align:justify"><span style="font-size:medium"><span style="font-family:Calibri,sans-serif"><span style="color:#000000"><strong><span style="color:black">Conclusion: </span></strong><span style="color:black">The most common risk-stratification tools for PE had modest discriminative power to predict short-term mortality in patients with acute PE and COVID-19. </span></span></span></span></p>
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