Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Quantitative comparison between 2D versus 3D late gadolinium enhancement for myocardial scar characterization – possible implication for intervention guidance and arrhythmogenic risk assessment
Session:
Posters (Sessão 6 - Écran 1) - Imagem 3 - RM Cardíaca e Cardiologia Nuclear
Speaker:
Pedro Freitas
Congress:
CPC 2022
Topic:
B. Imaging
Theme:
03. Imaging
Subtheme:
03.3 Cardiac Magnetic Resonance
Session Type:
Pósters Electrónicos
FP Number:
---
Authors:
Pedro Freitas; Sofia Mancelos; Pedro Lopes; Sérgio Maltés; Daniel Nascimento Matos; João Carmo; Salomé Carvalho; João Abecasis; Sara Guerreiro; Francisco Costa; Pedro Galvão Santos; Pedro Carmo; Diogo Cavaco; Pedro Adragão; António Miguel Ferreira
Abstract
<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><u>Background</u>: The characterization of myocardial scar tissue using late gadolinium enhancement (LGE) is a promising technique for refining the risk stratification of life-threatening arrhythmias and for planning interventions such as VT ablation.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><u>Objective</u>: The purpose of this study was to assess the impact of using a 2D- vs. 3D-LGE acquisition for the characterization of scar and arrhythmogenic substrate in patients with previous myocardial infarction.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><u>Methods</u><span style="color:#222222">: Patients with chronic myocardial infarction who underwent CMR for clinical proposes were included. Two LGE-sequences [1) breath-hold 2D-phase-sensitive inversion recovery; and 2) free-breathing 3D-inversion recovery with respiratory gating] were acquired 10 and 20 minutes after injection of 0.15mmol/kg gadolinium, respectively. Patients were excluded if the 3D dataset was considered of poor/intermediate quality by two expert readers, and if the 2D dataset presented significant misalignment between slices. Scar characterization was performed in both 2D- and 3D-LGE datasets using ADAS 3D software and included core mass, borderzone (BZ) mass, BZ channels (BZC) and BZC mass. </span></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><u><span style="color:#222222">Results</span></u><span style="color:#222222">: 133 patients with chronic myocardial infarction and with 2D- and 3D-LGE acquisitions were identified. The quality of the 3D-LGE dataset was poor in 18 patients (14%), intermediate in 40 patients (30%) and good in 75 patients (56%). Among these, 23 (31%) presented significant misalignment in the 2D dataset, precluding imaging processing. A final population of 52 chronic myocardial infarction patients – representing 52 pairs of 2D- and 3D-LGE datasets – was analyzed (mean age 62±11; 83% male; mean LVEF 40%±15%).</span></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><span style="color:#222222">Core infarct mass, BZ mass, and BZC mass using 2D- and 3D-LGE showed moderate correlation (Spearman rho values 0.59-0.67, p<0.001), with small systematic biases - Figure. BZ channels were detected in 44 patients (85%) by 3D-LGE and in 47 patients (90%) by 2D-LGE. Overall, the number of detected BZ channels was similar between 2D and 3D-LGE (BZ channels: 3 [IQR 1-4] vs 3 [IQR 1-4], p=0.179).</span></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="background-color:white"><span style="font-family:Calibri,sans-serif"><u><span style="color:#222222">Conclusion</span></u><span style="color:#222222">: Scar tissue characterization parameters with 2D- and 3D seem to be moderately correlated, but not interchangeable since significant differences in individual terms are frequently found. The clinical significance of these differences remains to be established.</span></span></span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site