Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
AMI due to left main coronary artery occlusion: a comparative multicenter study from 2008 to 2020
Session:
Comunicações Orais (Sessão 14) - Doença Coronária e Cuidados Intensivos 3 - Foco na Oclusão do Tronco Comum
Speaker:
Andreia Campinas
Congress:
CPC 2022
Topic:
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
Theme:
13. Acute Coronary Syndromes
Subtheme:
13.2 Acute Coronary Syndromes – Epidemiology, Prognosis, Outcome
Session Type:
Comunicações Orais
FP Number:
---
Authors:
Andreia Campinas; Marta Braga; André Alexandre; Ricardo Costa; André Frias; João Calvão; Mariana Brandão; João Carlos Silva; Marisa Silva Passos; Gustavo Pires de Morais; Bruno Brochado; André Luz; Catarina Gomes; João Silveira; Severo Torres
Abstract
<p style="text-align:justify"><span style="color:#000000"><span style="font-size:medium"><u><span style="font-family:"Times New Roman",serif">Introduction</span></u><span style="font-family:"Times New Roman",serif">: Acute myocardial infarction (AMI) due to left main coronary artery (LMCA) occlusion is a potentially fatal condition. We aimed to study a cohort of patients admitted in three terciary hospitals of Portugal with AMI due to LMCA occlusion.</span></span></span></p> <p style="text-align:justify"><span style="color:#000000"><span style="font-size:medium"><u><span style="background-color:white"><span style="font-family:"Times New Roman",serif">Methods</span></span></u><span style="background-color:white"><span style="font-family:"Times New Roman",serif">: We performed a retrospective multicenter study of 128 consecutive patients with AMI with LMCA occlusion submitted to immediate percutaneous coronary intervention (PCI) between January 1, 2008, until December 31, 2020. We sought to compare clinical characteristics, interventions and prognosis between an older group (from January 2008 to December 2012, N=28) and a contemporary group (from January 2017 and December 2020, N=48).</span></span></span></span></p> <p style="text-align:justify"><span style="font-size:medium"><u><span style="font-family:"Times New Roman",serif"><span style="color:#000000">Results</span></span></u><span style="font-family:"Times New Roman",serif"><span style="color:#000000">: No statistically significant differences were found in baseline risk factors between the two groups, except for hypertension (50% in group 1 vs 75% in group 2,p=0.027). There was no difference regarding presentation with cardiogenic shock (57.1% vs 64.6%,p=NS). The median time of symptoms to balloon was high but similar in both groups [180min (120-300) vs 210min (120-420),p=NS]. Group 1 had a lower pre-PCI thrombolysis in myocardial infarction (TIMI) flow (64.3% of the patients were classified as TIMI=0, while in group 2 only 33.3% presented TIMI=0, p=0.009). Radial access was more frequent in the contemporary group (33% vs 10.7%,p=0.028) as well as the administration of glycoprotein IIb/IIIa inhibitors (14.6%vs12%,p=0.004) and the rate of implantation of drug eluting stents (100% vs 63.2%, p=</span><span style="color:black">0.01</span><span style="color:#000000">). The use of mechanical cardiac support was higher in group 1 (82% vs 46%, p=0.002) but the intra-aortic pump balloon (IABP) was the only device available. In group 2, utilization of IABP, Impella pump, and extracorporeal membrane oxygenation was 37.5%, 20.8%, and 2.1%, respectively. The second </span><em><span style="color:#0e101a">antiplatelet</span></em><span style="color:#000000"> agent used was also different between groups (ASA/ticagrelor 75.6% preferred in group 2,p<0.001). In-hospital mortality (46.4% vs. 54.2%,p=NS) and 1-year cumulative mortality (17/28=60.7%vs 29/48=60.4%,p=NS) were high in both groups and no statistically significant differences in mortality rate at 12 months were found (log rank=0.572).</span></span></span></p> <p><span style="color:#000000"><u><span style="font-size:11pt"><span style="font-family:"Times New Roman",serif">Conclusion:</span></span></u><span style="font-size:11pt"><span style="font-family:"Times New Roman",serif"> The use of new drugs and more advanced devices was more common in the contemporary group but the median time to reperfusion remained unchanged. The last may explain why the prognosis of this condition remained dismal in this Portuguese cohort.</span></span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site