Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Acute myocarditis following mRNA COVID-19 vaccination
Session:
Sessão de casos clínicos
Speaker:
Daniel A. Gomes
Congress:
CPC 2021
Topic:
---
Theme:
---
Subtheme:
---
Session Type:
Sessão de Casos Clínicos
FP Number:
---
Authors:
Daniel A. Gomes; Rita Reis Santos; Pedro Freitas; Mariana Sousa Paiva; João Presume; Maria João Andrade; Jorge Ferreira; Marisa Trabulo; Miguel Mendes
Abstract
<p><span style="font-size:16px"><span style="font-family:Times New Roman,Times,serif">CASE REPORT:</span></span></p> <p><span style="font-size:16px"><span style="font-family:Times New Roman,Times,serif">A 32-year-old male, otherwise healthy except for an history of idiopathic myopericarditis 13 years earlier, was admitted with oppressive retrosternal chest pain.</span></span></p> <p><span style="font-size:16px"><span style="font-family:Times New Roman,Times,serif">He has had fever and generalized myalgia for two days, starting one day after the administration of the second dose of the mRNA COVID-19 vaccine. He denied any other symptoms and he was not taking any drugs or medications. His physical examination at admission was unremarkable except for the presence of fever.</span></span></p> <p><span style="font-size:16px"><span style="font-family:Times New Roman,Times,serif">The patient had elevated inflammatory parameters and myocardial biomarkers on blood analysis. The electrocardiogram demonstrated diffuse concave ST segment elevation (figure 1). Chest radiography and transthoracic echocardiography were normal. Cardiac magnetic resonance (CMR) mapping showed increased native T1 and T2 in mid anterior and lateral segments. Subepicardial late gadolinium enhancement was noted in the lateral wall (figure 2). Naso- and oropharyngeal polymerase chain reaction (PCR) for SARS-Cov-2 was negative in two different occasions. Given the high clinical suspicion and a CMR pattern consistent with acute myocarditis, coronary angiography was not performed.</span></span></p> <p><span style="font-size:16px"><span style="font-family:Times New Roman,Times,serif">Acute myocarditis was assumed. The patient was discharged 3 days after the admission and recommended against physical exercise in the following 3 to 6 months. A CMR for re-evaluation was scheduled within a 6-month period.</span></span></p> <p> </p> <p><span style="font-size:16px"><span style="font-family:Times New Roman,Times,serif">DISCUSSION:</span></span></p> <p><span style="font-size:16px"><span style="font-family:Times New Roman,Times,serif">Myocarditis is an inflammatory disease of the myocardium caused by a variety of infectious and non-infectious conditions, with viruses accounting for the majority of cases. Although some reports of myocarditis following vaccination exist, recent studies suggest its risk is not increased. Among mRNA COVID-19 vaccine recipients in clinical trials, systemic symptoms related to immunologic reactogenicity were frequent and mostly mild to moderate, with a median onset of 1 to 2 days after vaccine receipt. We can hypothesize that the immune response to the vaccine may be, at least in part, responsible for the recurrence of acute myocarditis in this particular patient.</span></span></p> <p> </p> <p><span style="font-size:16px"><span style="font-family:Times New Roman,Times,serif">CONCLUSIONS:</span></span></p> <p><span style="font-size:16px"><span style="font-family:Times New Roman,Times,serif">To our knowledge, this is the first report of acute myocarditis following mRNA COVID-19 vaccine administration. </span></span></p>
Video
Our mission: To reduce the burden of cardiovascular disease
Visit our site