Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Correlation of Body Mass Index, High-Sensitivity C-Reactive Protein and Prognosis in a Portuguese population with Coronary Artery Disease
Session:
Posters - E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
Speaker:
M. Raquel Santos
Congress:
CPC 2021
Topic:
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
Theme:
12. Coronary Artery Disease (Chronic)
Subtheme:
12.1 Coronary Artery Disease – Pathophysiology and Mechanisms
Session Type:
Posters
FP Number:
---
Authors:
M. Raquel Santos; Maria Isabel Mendonça; Margarida Temtem; Flávio Mendonça; João Adriano Sousa; Ana Célia Sousa; Sónia Freitas; Eva Henriques; Mariana Rodrigues; Sofia Borges; Graça Guerra; António Drumond; Roberto Palma Dos Reis
Abstract
<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Background:</strong> Pro-inflammatory cytokines produced by the obesity “status” can promote atherosclerosis evolution. Systemic inflammation with high-sensitivity C-reactive protein (hs-CRP) elevation has long been implicated in atherosclerosis and coronary artery disease (CAD) morbidity. <strong> </strong></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Aim:</strong> To investigate the correlation between the degrees of obesity (quantified by the body mass index (BMI), and hsCRP levels on the risk of CAD prognostic</span></span></p> <pre style="text-align:justify"> <span style="font-size:10pt"><span style="background-color:#f8f9fa"><span style="font-family:"Courier New""><strong><span style="font-family:"Calibri",sans-serif"><span style="color:black">Methods:</span></span></strong><strong> </strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">The study included a cohort of 1712 CAD patients aged 40-65 years old recruited from 2001 to 2018. </span></span></span><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">The primary outcome of this study was a composite of all-cause vascular morbidity (MACEs) including recurrent acute coronary syndrome (myocardial infarctus and unstable angina), coronary revascularization (coronary artery bypass grafting (CABG)/ percutaneous coronary intervention (PCI), rehospitalization for heart failure, ischemic stroke and dead (cardiovascular or all-cause mortality).Multivariate </span></span></span><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">Cox regression models were used to estimate the association between BMI, hsCRP on the risk of CAD events during a median 4.9±4.2 years follow-up. </span></span></span></span></span></span></pre> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Results:</strong> Comparing normal weight (BMI<24.99Kg/m2) with pre-obesity (BMI 25-29.99 kg/m2) patients, the <span style="color:black">Hazard ratio (HR) for events occurrence were similar either in the hsCRP</span><span style="color:black">≤</span><span style="color:black">3mg/L or in the hsCRP>3mg/L group. HsCRP>3mg/L increased significantly the risk, whatever the weight of the patient. The Hazard </span>ratio increased in patients with obesity (BMI≥30 kg/m2), even with normal HsCRP (Figure).</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Conclusions: </strong> CAD patients with mild obesity (BMI 25-29.99 kg/m2), compared with normal weight patients, did not present an increased risk of cardiovascular complications. Severe obesity in CAD patients presented increased cardiovascular risk in the follow-up. </span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">HsCRP>3mg/L was linked to a high cardiovascular risk, independent of the patient´s weight.</span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site