Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
PAMI score in acute heart failure patients: an additional value?
Session:
Posters - D. Heart Failure
Speaker:
Margarida G. Figueiredo
Congress:
CPC 2021
Topic:
D. Heart Failure
Theme:
11. Acute Heart Failure
Subtheme:
11.2 Acute Heart Failure – Epidemiology, Prognosis, Outcome
Session Type:
Posters
FP Number:
---
Authors:
Margarida G Figueiredo; Hélder Santos; Mariana Santos; Paula Sofia Paula; Inês Gracio Almeida; Micaela Neto; Catarina sá; Samuel Almeida; Joana Chin; Catarina Sousa; Luis Santos; João Tavares; Lurdes Almeida
Abstract
<p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><strong>Introduction:</strong></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"> PAMI score is a validated and established tool used to stratify and predict mortality risk in ST-elevation myocardial infarction patients. However, PAMI score capability to predict mortality in heart failure patients has not been validated.</span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><strong>Objective:</strong></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"> Validation of the PAMI score as a predictive tool of mortality in patients admitted with new-onset acute heart failure in a peripheral centre.</span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><strong>Methods</strong></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000">: Single-centre retrospective study, engaging patients hospitalized for </span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><em>de novo</em></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"> acute heart failure with reduced ejection fraction between 1/01/2010-31/12/2017. All patients’ clinical data were extracted at admission and the follow-up occurred in our centre. PAMI score was assessed at admission. Patients were divided in three groups, according to PAMI score: group A <5 points, B 5-8 points and C >8. All patients included in this analysis had a Killip-Kimball class ≥III, then this variable was excluded in the PAMI score calculation and the maximum punctuation was 11 points and the minimum 0 points. Chi-square and ANOVA tests were used to compare categorical and continuous variables. Logistic regression was performed to assess the relationship between the PAMI score and mortality, stroke incidence and re-admission for all causes after discharge. To evaluate the survival rates between groups Kaplan-Meier method was used (log-rank test).</span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><strong>Results</strong></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000">: 300 patients were included, 72.7% were male, mean age 67.42 ± 12.57 years with 41.68 ± 34.18 months of follow-up, left ventricular ejection fraction (LVEF) of 33.72 ± 12.19 and a mean GRACE score 4.33 ± 3.35. The three groups were similar regarding gender, rhythm at admission, LVEF, re-admission rates and stroke rates during the follow-up. As expected, the categorization of patients in three groups, revealed significant differences between the groups, namely in mean age (59.09 ± 10.74, 74.58 ± 6.51, 80.00 ± 3.59, </span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><em>p</em></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><0.001), PAMI score and survival rates (50.00%, 78.51%, 70.48%, </span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><em>p</em></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><0.001). Logistic regression revealed that PAMI score was a predictor of mortality (</span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><em>odds ratio</em></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"> 1.173, </span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><em>p</em></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><0.001, confidence interval 1.088-1.265), nevertheless it was not associated with re-admission for all causes (</span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><em>p</em></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000">=0.669) or stroke incidence (</span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><em>p</em></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000">=0.87). Mortality rates significantly increase with the PAMI score, with a Kaplan-Meier test of </span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><em>p</em></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><0.001 – figure 1. Curiously, Kaplan-Meier test showed significant differences, (</span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><em>p</em></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><0.001), between the three groups – figure 2. On the other hand, stroke incidence during the follow-up was not significant, (</span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><em>p</em></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000">=0.427), by the Kaplan-Meier method. </span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"><strong>Conclusions:</strong></span></span></span><span style="font-size:12pt"><span style="font-family:'Times New Roman'"><span style="color:#000000"> PAMI score, largely implemented in acute coronary syndromes, proved to be a relevant predictor of mortality in new-onset heart failure patients with reduced ejection fraction.</span></span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site