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07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
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31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
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34. Public Health and Health Economics
35. Research Methodology
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Cardiovascular risk and coronary artery disease burden in TAVI patients
Session:
Posters - G. Aortic Disease, Peripheral Vascular Disease, Stroke
Speaker:
Pedro Custodio
Congress:
CPC 2021
Topic:
G. Aortic Disease, Peripheral Vascular Disease, Stroke
Theme:
22. Aortic Disease
Subtheme:
22.4 Aortic Disease - Treatment
Session Type:
Posters
FP Number:
---
Authors:
Pedro Custódio; João Brito; Rui c Teles; Sérgio Madeira; Sílvio Leal; Afonso Oliveira; Mariana Gonçalves; Gustavo Mendes; Nelson Vale; Luís Raposo; Pedro Gonçalves; Henrique m Gabriel; Manuel de Sousa Almeida; Miguel Mendes
Abstract
<p> </p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Introduction</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"> Transcatheter aortic valve implantation (TAVI) is currently a therapeutic option for patients with severe aortic stenosis that are considered to be at high risk for surgical valvular intervention or for those over 75 years with intermediate risk. The majority of patients performs a coronary angiography (CA) prior to the procedure, in order to exclude significant coronary artery disease. We sought to characterize the cardiovascular risk profile and describe the epicardial coronary artery disease burden in patients that underwent CA.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"> Methods:</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Retrospective single center analysis of 517 consecutively included between 2009 and October 2020. Patients who underwent pre TAVR CA in the context of ACS or at other institution were excluded n=138. The cardiovascular risk (CVR) profile was assessed according to the presence of <em>diabetes mellitus</em> (DM), obesity (defined as BMI>30), hypertension, high blood cholesterol and tobacco smoking as was characterized any previous coronary artery intervention. The number of coronary lesions (defined as >50%stenosis) in the CA was collected.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">The correlation between CVR profile and coronary lesions in the CA was analyzed.</span></span></p> <p> </p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"> Results:</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">517 patients were included - average age of83,11(+/- 6.3 years), 55% male. The average of cumulative CVR factors was 2,19(+/-1.04) and 22 patients presented no single risk factor. </span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">A total of 164 patients had previous history of percutaneous coronary artery intervention and 86 coronary artery bypass surgery<u><span style="color:teal"> </span></u>(CABG) prior to the pre-TAVI CA (45 had both). The prevalence of angiographic disease was 28,2% in the remaining 312 patients. The correlation between risk factors and number of vessels with angiographically important lesions was weak(Table 1), although statistically significant (r2= 0.251, p=.000).</span></span></p> <p>Conclusion:</p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">The correlation between CV risk factors and coronary lesions seems weak in TAVI patients. The majority of patients without previous PCI or CABG presents no significant coronary artery lesions. </span></span></p>
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