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Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
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0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
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01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
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Aortic valve intervention for aortic stenosis and cardiac amyloidosis: a systematic review and meta-analysis
Session:
Posters - G. Aortic Disease, Peripheral Vascular Disease, Stroke
Speaker:
Diana De Campos
Congress:
CPC 2021
Topic:
G. Aortic Disease, Peripheral Vascular Disease, Stroke
Theme:
22. Aortic Disease
Subtheme:
22.4 Aortic Disease - Treatment
Session Type:
Posters
FP Number:
---
Authors:
Diana Decampos; Carolina Saleiro; Luis Pedro Abreu; Ana Botelho; Marco Costa; Lino Gonçalves; Rogério Teixeira
Abstract
<p>Background: Dual aortic stenosis (AS) and cardiac amyloidosis (CA) is a common presentation in the elderly. To support decision-making in aortic valve (AV) in CA-AS, we provide a comprehensive overview and a meta-analysis of outcomes after AV intervention.</p> <p> </p> <p>Methods: A systematic review of studies reporting clinical outcome after AV intervention in patients with CA-AS was conducted. The primary endpoint was all-cause mortality after AV intervention. Secondary endpoints included heart failure (HF) admissions and peri procedural complications. Reported event rates and hazard risk were pooled.</p> <p> </p> <p>Results: A total of four studies, encompassing 90 patients with CA-AS and 780 patients with lone AS were included for the present data meta-analysis. Eighteen deaths were reported during the follow-up. Weighted pooled analysis showed a non-significant higher risk of all-cause death in patients with CA-AS following either SAVR and/or TAVR (RR 2.68 95% CI 0.97 - 8.21, P=0.09, I2=76%). Among an homogenous TAVR population, the estimated risk of death in CA-AS patients was comparable with the lone AS population (RR 1.23 95% CI 0.77 - 1.96, P=0.39, I2=0%). Meta-analysis of HF hospitalizations and periprocedural complications was not possible because of the scarcity of data.</p> <p> </p> <p>Conclusion: The evaluation of current observational evidence suggests that the estimated risk of death after AV intervention - in particular TAVR - in CA-AS patients is comparable with the lone AS population. An AV intervention procedure is possibly not futile in CA-AS and should not be denied.</p>
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