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Epidemiology of infective endocarditis in Portugal, a populational study
Session:
CO 06 - Valvulopatias
Speaker:
Catarina Sousa
Congress:
CPC 2021
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
16. Infective Endocarditis
Subtheme:
16.2 Infective Endocarditis – Epidemiology, Prognosis, Outcome
Session Type:
Comunicações Orais
FP Number:
---
Authors:
Catarina Santos De Sousa; Paulo Nogueira; Fausto j Pinto
Abstract
<p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong>Introduction</strong>: Nationwide series have contributed to a reliable assessment of the changing epidemiology of infective endocarditis, even though conclusions are not uniform. </span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong>Objectives</strong>: We sought to use a recent populational series to describe the temporal trends on the incidence of infective endocarditis, its clinical and outcome results, in Portugal.</span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong>Methods</strong>: A nationwide retrospective temporal trend study on the incidence and clinical characterization of patients hospitalized with infective endocarditis, between 2010 and 2018, in Portugal.</span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong>Results</strong>: 7574 patients were hospitalized with infective endocarditis from 2010 to 2018 in Portuguese public hospitals. The average length of hospitalization was 29.3<span style="font-size:11.0pt">±</span>28.7days, predominantly men (56.9%), and 47.1% had between 60 and 79 years old. The most frequent infectious agents involved were <em>Staphylococcus</em> (16.4%) and <em>Streptococcus</em> (13.6%). During hospitalization, 12.4% of patients underwent heart valve surgery and 20% of the total cohort died. The annual incidence of infective endocarditis was 8.31 per 100000 habitants, being higher in men and increased with age. In-hospital mortality rate significantly increased during the analyzed period, the strongest independent predictors being ischemic or hemorrhagic stroke, sepsis, acute renal failure and older age.</span></span></p> <p><strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">Conclusions</span></span></strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">: In Portugal, between 2010 and 2018, the incidence of infective endocarditis presented a general growth trend with a deceleration in the most recent years. In addition, a significant rate of in-hospital complications, a mildly lower than expected stable surgical rate and a still high and growing mortality rate were observed.</span></span></p>
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