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Is balloon cryoablation effective in common pulmonary trunk?
Session:
CO 13- Atrial fibrilation
Speaker:
Pedro Silvério António
Congress:
CPC 2021
Topic:
C. Arrhythmias and Device Therapy
Theme:
05. Atrial Fibrillation
Subtheme:
05.4 Atrial Fibrillation - Treatment
Session Type:
Comunicações Orais
FP Number:
---
Authors:
Pedro Silvério António; Tiago Rodrigues; Joana Brito; Nelson Cunha; Sara Couto Pereira; Pedro Alves da Silva; Beatriz Valente Silva; Catarina Oliveira; Beatriz Garcia; Ana Margarida Martins; Patrícia Teixeira; Gustavo Lima da Silva; Nuno Cortez-Dias; Luís Carpinteiro; Fausto j Pinto; João de Sousa
Abstract
<p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">Introduction</span></span></span></strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">: Common pulmonary trunk (CPT) accounts for the most frequent pulmonary vein anatomical variation. The most frequent technique used for pulmonary vein isolation (PVI) is point-by-point radiofrequency, using cryoablation (CB) is still debatable. Some few studies have shown the feasibility and safety of CB in CPT atrial fibrillation (AF) patients (pts), most of them performed angio-CT prior to ablation. </span></span></span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">Purpose</span></span></span></strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">: To analyzed AF pts with and without CPT submitted to CB in regarding of success rate and safety.</span></span></span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">Methods</span></span></span></strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">: Single-center retrospective study of consecutive AF pts refractory to antiarrhythmics submitted to CB between 2017 and 2020. Before the procedure auriculography was performed in all pts to verify variations in pulmonary veins, however the procedure was not modify regarding the presence of CPT. Clinical records were analyzed to determine baseline characteristics, success rate and complications. Monitoring was performed with a 7-day event loop recorder at 3, 6 and 12 months and annually from the 2nd year. Success was defined by recurrence of AF (duration > 30seconds). Kaplan Meier survival curves were used to estimate the risk of events and the groups were compared using Chi-square and Mann-Whitney analysis.</span></span></span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">Results</span></span></span></strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">: A total of 232 pts (60±12 years, 68% males) underwent CB. 29 pts had CPT (28 - common left pulmonary trunk and 2 - common right pulmonary trunk). Baseline characteristics were similar between groups, except for CHA</span></span></span><sub><span style="font-size:6.5pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">2</span></span></span></sub><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">DS</span></span></span><sub><span style="font-size:6.5pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">2</span></span></span></sub><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">VASc score and prior cerebrovascular disease history which were higher in CPT pts (3±2 vs 2±2, p=0.001; 24.1% vs 6.8%, p=0.007, respectively). The mean baseline CHA</span></span></span><sub><span style="font-size:6.5pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">2</span></span></span></sub><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">DS</span></span></span><sub><span style="font-size:6.5pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">2</span></span></span></sub><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">VASc was 2±2 and the median post-CB follow-up was 135 (IQ 32-249) days. </span></span></span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">Both the 1 and 3 year arrythmic reccurrence after AF ablation was not significantly different when comparing CPT and non CPT group with a 3 year success rate of 95.8% in pts with CPV against 86.5% in pts without CPT (p=0.299).</span></span></span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:"Times New Roman",serif"><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">There was no difference between groups (p=0.296; p=0,164, respectively) regarding the time of the procedure, radiation dose and rate of complications. </span></span></span></span></span></p> <p style="text-align:justify"><strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">Conclusions</span></span></span></strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"><span style="color:black">: In our experience, balloon cryoablation for PVI is a safe and successful procedure in patients with CPT anatomical variation.</span></span></span></p>
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