Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Being a woman - a disadvantage in apical hypertrophic cardiomyopathy?
Session:
Painel 9 - Doença Valvular 7
Speaker:
Maria da Conceição Queirós
Congress:
CPC 2020
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
17. Myocardial Disease
Subtheme:
17.6 Myocardial Disease – Clinical
Session Type:
Posters
FP Number:
---
Authors:
Maria Conceição Queirós; Adriana Belo; on behalf of the Researchers of the Portuguese Registry of Hypertrophic Cardiomyopathy
Abstract
<p>Background: Recent data, including that from a Portuguese-based population registry, revealed that in Hypertrophic Cardiomyopathy (HCM) females appear to have a worse prognosis than males. In addition women are also more symptomatic. When particularizing to apical HCM (ApHCM) although data are also scarce, they seem to point in the same direction.</p> <p>Purpose: To study if there are particularities in women that allow them to differentiate from men regarding the presentation, clinical and prognostic evolution in a group of patients (pts) with ApHCM of large European country-based nationwide HCM registry.</p> <p>Material and methods: Of the 1090 pts of the national registry 10.3% had ApHCM with a mean age of 56.4±16.5 years. Of those 107 pts, 45 were women (13.5% of women included). During the follow-up (median of 3 years) 9.8% of the pts died. A comparative analysis (women versus (vs) men) was done regarding all registry data. Kaplan-Meier survival curves were assessed via log-rank test.</p> <p>Results: In this population women were more symptomatic at diagnosis (68.3 vs 44.1%; p=0.017), presenting more frequently with heart failure (HF) (43.2 vs 17.0%; p=0.006) and palpitations (27.0 vs 9.4%; p=0.028). They are also more symptomatic at first hospital evaluation (82.2 vs 39.3%; p<0.0001), but have less history of coronary heart disease (CAD) (0 vs 22.8%; p=0.001). Women have a higher degree of diastolic dysfunction (grade 2 – 73.7 vs 29.2%; p=0.008) on echocardiography and higher levels of B-type natriuretic peptide (BNP) at diagnosis (1080 vs 342pg/dL; p=0.008), but less often fibrosis on cardiac magnetic resonance imaging (MRI) (44.0 vs 92.2%; p<0.0001). At follow-up women remained more symptomatic (65.8 vs 30.9%; p=0.001), namely with more complaints of palpitations (26.3 vs 3.36%; p=0.002) and more frequent hospitalizations due to HF (37.5 vs 0%; p=0.042) There were no differences regarding mortality (9.1 vs 1.6%; p=0.075).</p> <p>Conclusions: Although there were no significant differences in survival (possibly due to the reduced number of events), we could say that in this population of pts with ApHCM, being a woman seems to be a disadvantage, as women are more symptomatic (since diagnosis and also at follow-up) and have higher BNP values, maybe because they have also, higher degrees of diastolic dysfunction. Compared to men, they only have less history of CAD and less often fibrosis on cardiac MRI, but these differences seem to have neither clinical nor prognostic relevance.</p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site