Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Hypertrophic cardiomyopathy in the elderly - does age matter?
Session:
Painel 10 - Doença Valvular 6
Speaker:
Maria da Conceição Queirós
Congress:
CPC 2020
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
17. Myocardial Disease
Subtheme:
17.6 Myocardial Disease – Clinical
Session Type:
Posters
FP Number:
---
Authors:
Maria Conceição Queirós; Adriana Belo; on behalf of the Researchers of the Portuguese Registry of Hypertrophic Cardiomyopathy
Abstract
<p>Background: Hypertrophic Cardiomyopathy(HCM) is usually diagnosed until the 5th decade. With aging, this diagnosis(dx) is increasing later in life. Some studies point out that in elderly, HCM has different clinical and morphological characteristic and a more(+) benign prognosis.</p> <p>Purpose: To evaluate in patients(pts) of a country-based nationwide HCM registry if the elderly (HCM diagnosed at or after 65 years old(≥65Y)) have clinical, morphological and prognostic differences than younger ones (less(<) than 65 years (<65Y) at dx).</p> <p>Methods: Of the 1033 patients(pts) studied (mean age of 53.3±16.6 years), 28.5% had ≥65Y. During the follow-up (median of 3 years) 3.5% of the pts died. A comparative analysis (≥65Y versus(vs) <65Y) was done with all registry data.</p> <p>Results: Elderly were + frequently(freq) women (p<0.001), + symptomatic(Symp) at dx (presenting + freq with heart failure(HF) (p<0.001) and angina (p=0.004)) and at 1<sup>st</sup> evaluation (p<0.001), had + history(hx) of atrial fibrillation (AF), hypertension, coronary disease (p<0.001), valvular disease (p=0.002), cerebrovascular and pulmonary diseases (p<0.001) but < familiar hx of HCM (p<0.001) and sudden death (p=0.011). On ECG had + AF (p<0.001), ST-T abnormalities (p=0.041) and left bundle block (p=0.024). On echocardiogram(echo) elderly had larger left atriums (p=0.041) and ventricles(LV) (p=0.027), + freq apical morphology (p=0.002), diastolic dysfunction (p=0.002), mitral regurgitation and higher(>) intraventricular gradient (IVg) (p<0.001). On Holter, they had + AF (p=0.003) and ventricular extrasystoles (p=0.027). Were + Symp on exercise (Exer) test(p=0.003) with < functional capacity(p<0.001). On Exer echo had > IVg in orthostatism(p=0.006) but on cardiac magnetic resonance imaging < maximum thickness of LV (p=0.004). They have + coronary artery disease on cardiac computed tomography (p=0.003) and > values of brain natriuretic peptide(p<0.001) at dx. Elderly were + treated with amiodarone (p=0.039), calcium and angiotensin II antagonist, ACE inhibitors, diuretics, anticoagulants and antiplatelet drugs(p<0.001). They underwent + pacemaker implantation but < implantable cardioverter defibrillator implantation(p<0.001).</p> <p>At follow-up, elderly overall mortality was > (p<0.001); they also remain + Symp (p<0.001), were + often hospitalized for angina (p=0.006) and HF (p<0.001) but < submitted to procedures (p=0.004) and had < risk of sudden death (p=0.011). Mortality predictors were different in the 2 groups (table). In multivariable modelling, age ≥65Y remained independently associated with overall mortality (HR 6.853 [2.579-18.212], p<0.001).</p> <p>Conclusions: In this population we can say that age matters, since elderly pts form a distinct group with a clearly different clinical presentation, evolution and morphological characteristics, but unlike other studies, they had worse prognosis.</p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site