Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Myocardial fibrosis is a predictor of AF in dilated cardiomyopathy – role of CMR
Session:
Painel 3 - Imagiologia Cardiovascular 3
Speaker:
Joana Margarida Nunes Rigueira
Congress:
CPC 2020
Topic:
B. Imaging
Theme:
03. Imaging
Subtheme:
03.3 Cardiac Magnetic Resonance
Session Type:
Posters
FP Number:
---
Authors:
Joana Rigueira; Rui Plácido; Luis Brás Rosário; Inês Aguiar Ricardo; Paula Campos; Cláudio David; Fausto José Pinto; Ana G. Almeida
Abstract
<p>Background: CMR Late gadolinium enhancement (LGE) has been found in about two-thirds of patients with dilated cardiomyopathy (DCM) and has been associated with ventricular arrhythmia and sudden death. The aim of this study was to assess, in patients (pts) with DCM, the relationship of LGE with the occurrence of atrial fibrillation (AF), which is a frequent complication of DCM.<br /> <br /> Methods: 72 consecutive pts (44±11 year-old, 29 men) with DCM were included, after exclusion of ischemic heart disease (coronary angiography or CCT), secondary cardiomyopathies (clinical and laboratory investigation), non-sinus rhythm and contraindications to CMR. Functional class and plasmatic NT-proBNP were assessed. All pts underwent CMR: a) short-axis SSFP for left atrial volume and left ventricle (LV) volumes and ejection fraction (EF); b) LGE presence (segmented inversion-recovery fast gradient-echo sequence); c) Global longitudinal strain using feature tracking (Circle cvi42). Mean follow-up period was 2.8+/1.8 years. The occurrence of AF was registered from the clinical records and from annual Holter monitoring during the follow-up period.<br /> <br /> Results: 56 pts were in NYHA class II and 16 in class III. Mean NT-proBNP was 551±380pg/ml, left atrial volume was 48.5±11.0 ml/m2, LV end-diastolic volume was 155±44mL/m2, EF was 34±8%, GLS was 16±2.1. LGE was found in 38 patients (67%) located in midwall, involving a mean of 6 segments per pt (range 3-11). During follow-up, AF episodes occurred in 31 pts. In comparison with pts without AF, pts with AF had higher NT-proBNP (836±110 vs 474±132 pg/ml, p=0.01), larger atrial volume (56.1±10.1 vs 38.2±9 ml/m2, p=0.002), larger LV end-diastolic volumes (162±31 vs 149±35ml/m2, p=0.03), lower GLS (14.9±2.1 vs 17.1±1.1) and more frequent LGE (p=0.0003). No differences were found in EF. Using multivariate analysis, the atrial size and the presence of LGE were independent predictors of AF episodes.<br /> <br /> Conclusion: In patients with DCM, both LGE and atrial size were independent predictors of AF, among functional class, LV volumes, GLS and NT-proBNP. These findings should be used for risk assessment and therapeutic decisions for AF prevention</p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site