Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
De novo heart failure patients – can we predict recovery?
Session:
Posters 4 - Écran 9 - Insuficiência Cardíaca
Speaker:
Rita Ribeiro Carvalho
Congress:
CPC 2019
Topic:
D. Heart Failure
Theme:
10. Chronic Heart Failure
Subtheme:
10.2 Chronic Heart Failure – Epidemiology, Prognosis, Outcome
Session Type:
Posters
FP Number:
---
Authors:
Rita Ribeiro Carvalho; Sara Lopes Fernandes; Luís Graça Santos; Fernando Montenegro Sá; Catarina Ruivo; Joana Correia; Joana Guardado; Joao Morais
Abstract
<p><strong>Introduction:</strong> Left ventricular function recovery (LVFR) in the setting of heart failure (HF) is known to be associated with better outcomes. However, few and inconsistent data exists about predictors of LVFR in <em>de novo</em> HF patients. The aim of the present study is to identify clinical, analytical and echocardiographic predictors of LVFR in a cohort of HF patients followed in advanced HF consult.</p> <p><strong>Methods:</strong> A single-center study was designed, with a cohort of 329 patients regularly followed from Jan/2010 until Nov/2018. 240 patients were excluded, due to the impossibility to identify the onset of HF syndrome or absence of follow-up data. 18 patients were also excluded as they were submitted to resynchronization therapy. For the studied population with the remaining 70 patients, we analysed demographic, clinical, analytical and echocardiographic parameters. The primary endpoint (LVFR) was defined as an increase in left ventricular ejection fraction (LVEF) of 15%. Predictors of the endpoint were assessed using χ<sup>2</sup> or Fisher’s exact tests, accordindly, and known confounders were assessed with multiple logistic regression. Missing data, assumed completely at random, were assessed through multiple imputation. Analysis with STATA14.2 (α=0.05).</p> <p><strong>Results: </strong>The studied population was 81.4% (n=57) male, and had a mean age of 63.5±12.6 yo. 32 patients (45.7%) were already treated with neurohormonal antagonist drugs at the HF diagnosis.</p> <p>Hemodynamic profile at HF diagnosis was congestive in 81.4% (n=57). Etiology was ischemic in 27.1% (n=19), ethanolic in 27.1% (n=19), tachycardiomyopathy in 15.7% (n=11), familiar in 8.6% (n=6) and unknown in 21.4% (n=15).</p> <p>45.7% (n=32) of population studied experienced LVFR within a follow-up period of 197,8 person-years and an incidence rate of 1.6 cases per 10 person-years of follow-up. Mean time up to the recovery was 22.2 months.</p> <p>Univariate analyses for predictors of LVEF are presented in the table. Treatment with neurohormonal antagonist drugs was associated to less probability of LVFR, even when controlled for age and for the presence of HTN with an adjusted OR of 0.29 (p=0.036, 95% CI 0.09-0.92). Ischemic etiology was also associated with less probability of LVFR (OR 0.26, p=0.015, 95% CI 0.09-0.76). No predictors of LVFR were found regarding biochemical data (Hb, GFR, troponin, BNP, iron deficiency). The presence/absence of LBBB and a QRS≥130 were not associated with LVFR. Echocardiographic parameters such as LVTDD, LVEFgravity or presence/absence of LA dilation at the diagnosis, were also not predictive of LVFR.</p> <p><strong>Conclusions: </strong>In this cohort, almost half of the patients experienced LVFR, with an incidence rate of 1.6 cases per 10 person-years of follow-up. According to our sample, we were unable to find predictors of LVFR. Only previous treatment with neurohormonal antagonists drugs and ischemic etiology were significantly associated with less probability of LVFR.</p>
Our mission: To reduce the burden of cardiovascular disease
Visit our site