Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Resynchronization in heart failure patients: who will develop atrial fibrillation?
Session:
Posters 4 - Écran 9 - Insuficiência Cardíaca
Speaker:
James Milner
Congress:
CPC 2019
Topic:
D. Heart Failure
Theme:
10. Chronic Heart Failure
Subtheme:
10.2 Chronic Heart Failure – Epidemiology, Prognosis, Outcome
Session Type:
Posters
FP Number:
---
Authors:
James Milner; J Almeida; André Azul Freitas; João André Ferreira; Patrícia M. Alves; Ana Vera Marinho; Natália António; Miguel Ventura; João Cristóvão; Luis Elvas; Lino Gonçalves
Abstract
<p><strong>Background:</strong> Heart failure (HF) patients have a predisposition for atrial fibrillation (AF), resulting in increased morbidity and mortality. However, there is scarce data regarding predictors of development of AF among patients submitted to cardiac resynchronization therapy (CRT), which could have significant therapeutic implications. </p> <p><strong>Aims:</strong> To investigate potential risk factors for AF development in a cohort of HF patients submitted to CRT.</p> <p><strong>Methods and population:</strong> Single-center retrospective study of 274 patients submitted to CRT, in sinus rhythm at the time of the device implantation. The population was divided into two groups: A) those who developed AF (N=54) and B) those who do not present AF during long term follow up (N=220). Median follow-up was 2.9± 1.5 years after CRT. Baseline demographic, clinical and echocardiographic characteristics were compared. </p> <p><strong>Results: </strong>During long term follow-up, 20% of patients developed AF. Age was similar in both groups (65±11), with a higher prevalence of males among patients presenting AF (82% vs 64%, p=0.013). Prevalence of other comorbidities, including arterial hypertension, hyperlipidemia, diabetes and chronic kidney disease did not differ significantly between groups, and patients were treated with disease-modifying HF drugs in similar proportions. Patients had HF of non-ischemic etiology in 60% of cases in both groups, with a higher prevalence of patients with NYHA functional class III or IV among patients who present AF at any time during follow up (89% vs 74%, p=0.033). No inter-group difference was found regarding electrocardiographic (including heart rate, QRS duration and left bundle branch block pattern) and echocardiographic parameters (including left ventricular ejection fraction, left ventricular volumes and left atrium diameter). Despite no difference in all-cause mortality between groups, there was a trend towards more readmissions due to acute decompensated HF in AF patients (38% vs 25%, p=0.072). After multivariate analysis, male gender and NYHA III or IV previously to resynchronization remained as independent predictors of AF during follow-up (OR 2.82, 95% CI 1.26-6.40, p=0.012, and OR 3.15, 95% CI 1.16-8.56, p=0.025, respectively).</p> <p><strong>Conclusions:</strong> A significant proportion of HF patients submitted to CRT develop AF during follow-up, and males and patients in higher NYHA functional classes have a higher risk of AF in this population. The recognition of predictors of AF in HF patients is of paramount importance for the prevention and early identification of AF, which may help avoid HF decompensation and allow a timely treatment of AF.</p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site