Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
New aproaches in cardiopulmonary exercise testing in congenital heart disease adults
Session:
Posters 4 - Écran 6 - Miscelânea
Speaker:
Tânia Branco Mano
Congress:
CPC 2019
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
20. Congenital Heart Disease and Pediatric Cardiology
Subtheme:
20.2 Congenital Heart Disease – Epidemiology, Prognosis, Outcome
Session Type:
Posters
FP Number:
---
Authors:
Tânia Branco Mano; António Valentim Gonçalves; Sílvia Aguiar Rosa; Ana Figueiredo Agapito; Lidia De Sousa; José Alberto Oliveira; André Viveiros Monteiro; Sofia Silva; Sandra Alves; Maria De Fátima Pinto; José Fragata; Rui Cruz Ferreira
Abstract
<p>Background: In recent years, new parameters for ventilatory efficiency assessment in Cardiopulmonary Exercise Testing (CPET) have demonstrated to predict prognosis. However, their value in Congenital Heart Disease (CHD) population remains unclear.</p> <p>Objectives: The aim was to compare functional capacity in different types of CHD, assessed by CPET, and to investigate an association between CPET parameters and cardiovascular outcome.</p> <p>Methods: Retrospective analysis of adult CHD patients who underwent CPET and followed up for at least one year. Primary endpoint: death from any cause. Combined secondary endpoint: death from any cause and cardiac hospitalization. CPET parameters were evaluated and determined endpoints predictors.</p> <p>Results: We analyse 286 CPET: 50,3% males, mean age of 35.6 ± 9.4 years and of 3.89 ± 2.3 years of follow-up (FU). Etiology: Tetralogy of Fallot 36% (N=103); complex defects 19,6% (N=56); transposition of the great arteries (TGA) after Senning or Mustard procedures 14,3% (N=41); right ventricular outflow tract obstruction 8% (N=23), left heart valve disease 4,5% (N=13); Eisenmenger syndrome 3,1% (N=6) and congenitally corrected TGA 2,8% (N=8). The primary and secundary endpoints were achieved in 9 (3.2%; at 9 ± 0,12 years) and 75 patients (25.2%; at 6.28 ± 0.27 years) in the follow-up. Predictors of outcomes evaluated by Cox analysis are represented in Table 1. In multivariated analysis higher cardiorespiratory optimal point (HR 1.104; p=0.007) and and lower VO2 (HR 0.806; p=0.029) were predictors of primary endpoint. In multivariated analysis, exercise oscillatory breathing (EOB) (HR 4.766, p<0.0001), male gender (HR 3.087, p<0.0001), inicial oxyhemoglobin saturation (SpO2) (HR 0.937; p=0.011) and age (HR 1.040; p=0,013) were the predictors of secondary endpoint. The strongest predict power for primary endpoint was observed for SpO2 in maximal effort with an area under the curve (AUC) of 0.859 and initial SpO2 0.783, followed by cardiorespiratory optimal point (AUC 0.757), rest End-Tidal Carbon Dioxide (ETCO2, AUC 0.755) and pVO2 (AUC 0.783)</p> <p>Conclusion: In CHD adult patients, not only SpO2, pVO2 and chronotropic index, but also non-traditional parameters as cardiorespiratory optimal point, ETCO2 and EOB can predict all-cause mortality and hospitalization for cardiac cause.</p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site