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Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
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A. Basics
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01. History of Cardiology
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05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
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20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
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28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
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34. Public Health and Health Economics
35. Research Methodology
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Functional capacity, but not left ventricle diastolic dysfunction or BNP, is associated with quality of life in HFpEF patients
Session:
Posters 3 - Écran 9 - Imagiologia Cardiovascular
Speaker:
Maria Trêpa
Congress:
CPC 2019
Topic:
D. Heart Failure
Theme:
10. Chronic Heart Failure
Subtheme:
10.7 Chronic Heart Failure - Other
Session Type:
Posters
FP Number:
---
Authors:
Maria Trêpa; Cristine Schimdt; Raquel Baggen Santos; Marta Fontes Oliveira; Ricardo Costa; André Dias De Frias; Daniel Moreira-Gonçalves; Jose Oliveira; Vasco Alves Dias; Mário Silva Santos; Severo Torres
Abstract
<p>Introduction</p> <p>Heart Failure with preserved ejection fraction (HFpEF) is a heterogeneous systemic disease that affects predominantly the elderly and requires tailored therapies. The Minnesota Living with Heart Failure questionnaire (MLHFQ) is validated in HFpEF to measure quality of life (QoL), an increasingly important outcome in this population. However, the relation of QoL with functional capacity and cardiac function has not been defined before. We aimed to study these correlations. </p> <p>Methods</p> <p>Prospective, cross-sectional study of patients with HFpEF (n=24) . MLHFQ was done by interview. Patients were divided into two groups according to their median MLFHQ Score. We compared (1) cardiorespiratory fitness assessed by pulmonary gas exchange analysis during a 6-minute walk test (6MWT), (2) anthropometric measurements, (3) BNP value; (4) LV diastolic function by echocardiographic.</p> <p>Results</p> <p>The mean age of patients included was 76±6 yo, 70% were female and 51% were obese. The MLHFQ total median score was 25 (interquartile range: 5-37). 58% of patients had score bellow 25, representing a good QoL, while 42% had score over 25 representing a poorer QoL. The groups had no significant differences regarding age or sex, baseline cardiovascular risk factors or NYHA Class</p> <p>Echocardiographic evaluation didn’t show differences in diastolic function between the two QoL groups (left atrial indexed volume: 42ml/m2 vs 43 ml/m2, p=0.7; E/e’: 14 vs 15, p=0.5; tricuspide maximum regurgitant velocity: 31 cm/s vs 33 cm/s, p=0.7).</p> <p>No difference in the BNP plasma concentrations was observed (265 pg/mL vs 323 pg/mL, p=0.05).</p> <p>Regarding functional capacity, patients with lower QoL had a significantly lower functional capacity indicated by oxygen peak uptake (peak VO2: 12 ml/min/kg vs 9.9 ml/min/kg, p=0.01) and 6-minute walking distance (344 meters vs 266 meters, p= 0.03).</p> <p>Conclusion</p> <p>HFpEF patients with worse QoL have reduced functional capacity, but no differences on diastolic function and BNP plasma concentrations. Our results emphasize the systemic nature of this disease arguing in favour of a less cardiocentric approach when aiming to improve QoL of these patients.</p>
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