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Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
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A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
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01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
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19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
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Clinical and Hemodynamic 5-year mortality predictors in patients with pulmonary hypertension
Session:
Posters 2 - Écran 10 - Circulação / Embolia Pulmonar
Speaker:
Nzinga Carolina Manuel André
Congress:
CPC 2019
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
Subtheme:
21.2 Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure – Epidemiology, Prognosis, Outcome
Session Type:
Posters
FP Number:
---
Authors:
Nzinga André; Rui Plácido; Tatiana Guimarães; João Pedro Ribeiro Agostinho; Joana Rigueira; Inês Aguiar Ricardo; Nelson P. Cunha; Pedro Silvério António; Pedro Morais; Ana Mineiro; Susana Martins; Nuno Lousada; Fausto José Pinto
Abstract
<p>Introduction: Pulmonary hypertension (PH) is associated with high morbidity and mortality rates, making early prognostic stratification essential. Although several predictors of mortality have already been established, the emergence of novel therapies and the evolution in the management of these patients makes it urgent to reassess and validate prognostic markers.<br /> Purpose: To ascertain clinical and hemodynamic 5 year mortality predictors in patients with the diagnosis of PH.<br /> Methods: It was made a retrospective single center study (PH reference center) of consecutive patients with hemodynamic diagnosis of PH. At-diagnosis demographic and clinical data [WHO functional class and presence of right-sided heart failure (HF) signs], non-invasive diagnostic tests [6-minute-walk test (6MWT) and carbon monoxide diffusion capacity (DLCO)] and hemodynamic parameters [right atrial pressure (RAP) and mean pulmonary artery pressure (MPAP)] were collected. The association of these variables with any cause 5-years mortality was evaluated using Kaplan-Meier survival analysis and Cox regression analysis.<br /> Results: A total of 176 patients were included, 69.9% (N = 123) female, with a median age of 68 years (IQR: 24). Based on the clinical classification, 28.4% (N = 50) belonged to group 4, 27.3% (N = 48) to group 1, 23.3% (N = 40 to group 2, 17.6% (N = 31) to group 3 and 3.4% (N = 6) to group 5. The 5-year mortality rate from any cause was 27.3%. Were identified as predictors of mortality being of male gender (p <0.001) and had group 2, 3 and 5 PH (p 0.017, p 0.004, p 0.042; versus group 4 and 1).<br /> Conclusion: In this study, male sex and group 2, 3 and 5 PH were identified as 5 year mortality predictors. These results allow the identification of patients groups who may benefit from earlier multidisciplinary therapeutic interventions.<br /> </p>
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