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Curso de Atualização em Medicina Cardiovascular 2019
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Physical activity predicts arterial stiffness in resistant hypertension
Session:
Posters 1 - Écran 8 - Enfermagem/Técnicos
Speaker:
Catarina Garcia
Congress:
CPC 2019
Topic:
I. Hypertension
Theme:
27. Hypertension
Subtheme:
27.7 Hypertension - Other
Session Type:
Posters
FP Number:
---
Authors:
Catarina Garcia; Susana Lopes; Daniela Figueiredo; Ana C Gonçalves; Ilda P Ribeiro; João L Viana; Susana Bertoquini; José Oliveira; Mesquita Bastos; Jorge Polónia; Fernando Ribeiro; Alberto J Alves
Abstract
<p><strong>Background:</strong> Arterial stiffness has been inversely associated with physical activity (PA) and cardiorespiratory fitness (CRF) among healthy and clinical populations. However, little is known about this relationship among patients with resistant hypertension. Therefore, we aimed to understand if arterial stiffness is associated with PA levels and CRF among resistant hypertension patients.</p> <p><strong>Methods:</strong> In this cross-sectional study, 24 patients (10 men, 14 women; age, 57.9±8.2 years; weight, 77.0±10.7 kg; body mass index, 29.0±3.5 kg/m²) with resistant hypertension were recruited. Outcome measures included VO<sub>2</sub>peak, which was evaluated with a submaximal step test; carotid-femoral pulse wave velocity (cf-PWV), which was measured by applanation tonometry; and weekly PA evaluated by triaxial accelerometry. Participants used the accelerometer in 6.5±0.8 days, accumulating a total time of 5569.2±953.5 minutes. Correlation and linear regression analyses were conducted to examine the relationship between variables and potential predictors.</p> <p><strong>Results:</strong> A significant negative correlation was found between light PA (2461.7±819.2 minutes per week) and cf-PWV (9.6±3.0 m/s, <em>r</em>=-0.551, <em>p</em>=0.005). cf-PWV was also inversely correlated with total PA (2656.9±841.6 minutes per week, <em>r=</em>-0.565, <em>p=</em>0.004). In contrast, there was no association of cf-PWV with MVPA (195.3±127.3 minutes per week, <em>r=</em>-0.192, <em>p=</em>0.369), sedentary time (2912.3±796.4 minutes, <em>r=</em>0.295, <em>p=</em>0.192) and CRF (34.0±6.3 mLO<sub>2</sub>.kg<sup>-1</sup>.min<sup>-1</sup>, <em>r=</em>-0.026, <em>p=</em>0.905). Total PA per week was the only significant predictor of cf-PWV among this clinical population (<em>β</em><em>=-0.565</em><em>,</em> <em>p=</em>0.004).</p> <p><strong>Conclusion:</strong> In resistant hypertension patients, arterial stiffness was associated with light PA and total PA, but not CRF. Moreover, total PA was a predictor of arterial stiffness.</p>
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