Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Coronary allograft vasculopathy after cardiac transplantation: prevalence, prognostic and risk factors
Session:
Posters 4 - Écran 01 - Isquemia/SCA
Speaker:
André de Lima Antunes
Congress:
CPC 2018
Topic:
H. Interventional Cardiology and Cardiovascular Surgery
Theme:
26. Cardiovascular Surgery
Subtheme:
26.8 Cardiovascular Surgery - Transplantation
Session Type:
Posters
FP Number:
---
Authors:
Antunes de Lima Antunes; Carlos Branco; David Prieto; Carlos Pinto; Manuel Antunes
Abstract
<p><strong>Introduction:</strong> Coronary allograft vasculopathy (CAV) is still a serious long-term complication after cardiac transplantation.</p> <p><strong>Purpose:</strong> To evaluate the prevalence of CAV in a single institution, its impact on survival and to explore associated risk factors.</p> <p><strong>Methods:</strong> From November-2003 through June-2016, 316 patients were submitted to cardiac transplantation. After excluding those with paediatric age (n=8), those with previous renal or hepatic transplantation (n=2) and those who didn’t survive the first year after cardiac transplantation (n=40), the study population resulted in 266 patients. Forty two patients (15.7%) with CAV, diagnosed by a new <u>></u>50% coronary artery stenosis in any vessel during follow-up, were compared with a non-CAV group.</p> <p><strong>Results:</strong> Both groups share de same median age (54<u>+</u>10years). Recipient male sex predominated in the CAV group (93% vs. 74%, p=0.017), as did ischemic etiology (52% vs. 37%, p=0.032). Although not reaching statistical significance, CAV patients also had more dyslipidemia (60% vs. 50%, p=0.368), history of smoking (52% vs. 44%, p=0.227) and peripheral vascular disease (45% vs. 29%, p=0.071). The incidence of celular acute rejection 1R is more present in CAV group (69% vs. 60%) such as 2R or 3R (29% vs. 27%, p=0.452). Prolonged use of inotropic support and mechanical assistance after cardiac transplantation were comparable between groups. Survival between CAV and non-CAV group was comparable at 5-year (91% vs. 85%), but tended to be lower for CAV patients in 10-year interval (52% vs. 73%, p=0.727).</p> <p><strong>Conclusion:</strong> This data confirms CAV as a common long-term complication following cardiac transplantation. Although short to mid-term survival seems not to be affected by CAV, long-term survival appears lower, hence a longer follow-up is needed.</p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site