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CPC 2018
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Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
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0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
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K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
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N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
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01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
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A comparison study between 2-dimensional and 3-dimensional echocardiographic markers of myocardial fibrosis in hypertrophic cardiomyopathy
Session:
Posters 3 - Écran 02 - Miocárdio e Pericárdio
Speaker:
Isabel Campos
Congress:
CPC 2018
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
15. Valvular Heart Disease
Subtheme:
15.3 Valvular Heart Disease – Diagnostic Methods
Session Type:
Posters
FP Number:
---
Authors:
Isabel Durães Campos; Rita Passos; Catarina Vieira; Jorge Marques; Vitor Hugo Pereira
Abstract
<p><strong>Introduction: </strong>Hypertrophic Cardiomyopathy (HCM) is a primary disease of the sarcomere that significantly increases the risk of Sudden cardiac death (SCD). Recent evidence shows that myocardial fibrosis quantified by Cardiac Magnetic Resonance (CMR) with late gadolinium enhancement (LGE) may be an additional criterion for SCD risk stratification. However, the availability of this exam is limited and other markers of fibrosis would be useful in the long-term follow-up of patients with HCM.</p> <p><strong>Objective: </strong>In this sense, the main aim of this work is to identify echocardiographic markers of myocardial fibrosis and assess if three-dimensional (3D) echocardiographic tools, in particular 3D-strain present any added value to two-dimensional (2D) echocardiopraphy to predict fibrosis.</p> <p><strong>Methods: </strong>For this purpose, all HCM outpatients under follow-up in the cardiology department of a single center that had previously performed CMR-LGE were proposed to perform a full transthoracic echocardiography. A group of twenty-five individuals were enrolled and divided in LGE-positive and LGE-negative subgroups.</p> <p><strong>Results: </strong>LGE-positive patients had significantly higher interventricular septum thickness (<em>p</em>=0.017), left atrium diameter (<em>p</em>=0.006) and decreased 2D global longitudinal strain (GLS) (<em>p</em>=0.005). Parameters of 3D strain such as area, longitudinal, circumferential and radial strains also had strong correlations with LGE. However, 2D-GLS was the best discriminator for the presence of fibrosis (sensitivity of 88.2% and specificity of 87.5%). The assessment of 2D-GLS in patients with atrial fibrillation was possible using multiplanar single-beat acquisitions.</p> <p><strong>Conclusion: </strong>Our study is, to our knowledge, the first head-to-head comparison between 2D and 3D to predict myocardial fibrosis. Results shows that 3D-strain parameters did not provide any added value in comparison with 2D-strain to predict myocardial fibrosis in patients with HCM. However, the use of 3D technology was very helpful to quantify strain in patients with atrial fibrillation.</p>
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