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Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
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A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
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01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
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emporal trends in short-term all-cause mortality according to gender in acute coronary syndromes
Session:
Posters 2 - Écran 01 - Isquemia/SCA
Speaker:
Ana Teresa Timóteo
Congress:
CPC 2018
Topic:
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
Theme:
13. Acute Coronary Syndromes
Subtheme:
13.2 Acute Coronary Syndromes – Epidemiology, Prognosis, Outcome
Session Type:
Posters
FP Number:
---
Authors:
Ana Teresa Timóteo; Sílvia Aguiar Rosa; António Valentim Gonçalves; Tiago Mendonça; Ramiro Sá Carvalho; Maria De Lurdes Ferreira; Rui Cruz Ferreira
Abstract
<p>Background: There is a differential rate in mortality according to gender after acute coronary syndromes (ACS). We sought to evaluate the temporal trends of all-cause mortality in short-term after ACS according to gender.</p> <p>Methods: Patients were prospectively included between 2005 and 2017 in a single-center registry of ACS. We analyzed in-hospital and 30-day mortality after ACS in each year of admission according to gender and analyzed also the evolution in terms of difference. The impact of gender was studied by multivariate regression analysis, adjusted for the year of admission.</p> <p>Results: We included 3990 patients, with a mean age of 64 ± 13 years, 72% males and 65% with STEMI. There was 5.3% of in-hospital mortality and 6.1% of 30-day mortality in the overall population. Since 2005, we observed that female gender had higher in-hospital and 30-day mortality, but the difference between genders was variable over the years, without a clear decline (Figure). In univariate analysis, female gender was a predictor of short-term outcome (OR 1.67, 95%CI 1.26-2.22, p<0.001 for in-hospital mortality, and OR 1.59, 95%CI 1.22-2.09, p=0.001 for 30-day mortality), but in multivariate analysis, female gender was no longer an independent predictor (OR 1.00, 95%CI 0.69-1.45, p=0.994 for hospital mortality, and OR 0.97, 95%CI 0.70-1.37, p=0.885 for 30-day mortality), including adjustment for the year of admission. The independent predictors of outcome were age, previous revascularization, heart rate, systolic blood pressure, Killip class, presentation as ST-elevation acute myocardial infarction, double antiplatelet therapy, renin-angiotensin-aldosterone system drugs, beta-blocker and statin use and percutaneous coronary intervention.</p> <p>Conclusions: Women have worst outcome in short-term after ACS and there is no trend for a decline. However, this bad prognosis is dependent of other variables with impact in outcome. </p>
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