Login
Search
Search
0 Dates
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Predictors of arrhythmias in adults with dextro-transposition of the great arteries
Session:
CO 16 - Congénitos
Speaker:
Madalena Coutinho Cruz
Congress:
CPC 2018
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
20. Congenital Heart Disease and Pediatric Cardiology
Subtheme:
20.2 Congenital Heart Disease – Epidemiology, Prognosis, Outcome
Session Type:
Comunicações Orais
FP Number:
---
Authors:
Madalena Coutinho Cruz; Ana Figueiredo Agapito; Mário Martins Oliveira; José Alberto Oliveira; Lidia De Sousa; Sérgio Laranjo; André Viveiros Monteiro; Luisa Moura Branco; Maria De Fátima Pinto; Rui Cruz Ferreira
Abstract
<p><strong>Introduction:</strong> With recent advances in management of congenital heart disease (CHD), more patients with d<em>extro</em>-transposition of the great arteries (d-TGA) survive until adulthood. Information about the long-term complications of the disease and its treatment is scarce. We aimed to characterize a population of d-TGA patients and search for predictors of arrhythmic events.</p> <p><strong>Methods:</strong> Demographic data and clinical information (transthoracic echocardiography, cardiopulmonary exercise test, cardiac magnetic resonance (CMR), cardiac surgeries/interventions and adverse events) of all consecutive d-TGA patients referred to a single tertiary center’s adult CHD outpatient clinic between February/1972 and May/2016 was collected. Sustained supraventricular and ventricular arrhythmias (SVT and VT), sinus node disease (SND) and second degree (or higher) heart block (AVB) arising during follow-up (FU) were noted. Predictors of arrhythmias were assessed with logistic regression analysis.</p> <p><strong>Results: </strong>58 patients (58.6% male, age at first visit 21.8 ± 5.7 years) were included. 43.1% of patients had additional heart defects and 96.5% had been submitted to surgery during childhood (28 atrial switch, 17 arterial switch, 13 other types of surgery). 48.3% of patients were submitted to > 1 surgery. During a mean FU of 9.8 ± 7.7 years, 34.5% of patients experienced at least 1 arrhythmia (13 SVT, 3 VT, 8 AVB, 4 SND), with 8 patients having more than one type of arrhythmia. Mean age at first arrhythmic event was 22.5 ± 12.8 years. 13.8% of patients implanted a permanent pacemaker and 5.2% a cardioverter defibrillator. The presence of arrhythmias was significantly associated with the occurrence of heart failure (OR 14.400 95% CI 1.594-130.093 p 0.018), but not with hospitalization for cardiac cause or death. Variables that were significantly associated with the appearance of arrhythmias were: NYHA class (OR 3.179 p 0.027), peak exercise heart rate (HR) (OR 0.973 95% p 0.046), tissue Doppler tricuspid s’ (OR 0.396 p 0.084), systemic ventricle ejection fraction (EF) by CMR (OR 0.932 p 0.082), non-systemic ventricle end-diastolic volume by CMR (OR 1.061 p 0.022), non-systemic ventricle end-systolic volume by CMR (OR 1.112 p 0.009), non-systemic ventricle EF by CMR (OR 0.834 p 0.009), atrial switch surgery (OR 3.167 p 0.055) and number of heart surgeries (OR 1.702 p 0.066). Peak exercise HR and non-systemic ventricle EF showed a tendency for independently predicting the appearance of arrhythmias during FU (p 0.063 and 0.090, respectively).</p> <p><strong>Conclusion:</strong> In this population of patients with d-TGA, arrhythmias were a highly prevalent event and were associated with heart failure. This study highlights the importance of exercise and imaging tests, as well as previous surgeries to predict the occurrence of arrhythmias.</p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site