Login
Search
Search
0 Dates
2025
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
CPC 2025
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Acute Coronary Syndrome in Young Women: Risk Factors and Long-Term Prognosis
Session:
SESSÃO DE POSTERS 17 - DIFERENÇAS ENTRE SEXOS NA MEDICINA CARDIOVASCULAR
Speaker:
Liliana Brochado
Congress:
CPC 2025
Topic:
K. Cardiovascular Disease In Special Populations
Theme:
30. Cardiovascular Disease in Special Populations
Subtheme:
30.2 Cardiovascular Disease in Women
Session Type:
Cartazes
FP Number:
---
Authors:
Liliana Brochado; Oliveira Baltazar; Mariana Martinho; Bárbara Ferreira; Diogo Cunha; João Luz; Nazar Ilchyshyn; Adriana Silva; Ana Rita Pereira; Hélder Pereira; Paula Fazendas
Abstract
<p style="text-align:justify"><strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">Introduction: </span></span></strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">Heart disease mortality rates in young women are rising. Despite this, there are significant gaps in knowledge regarding the prevention and treatment of ischemic heart disease in young adults, particularly women, who remain underrepresented in clinical trials.</span></span></p> <p style="text-align:justify"><strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">Purpose: </span></span></strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">Describe the demographic and clinical characteristics of young women hospitalized with Acute Coronary Syndrome (ACS) and assess major adverse cardiovascular events (MACE).</span></span></p> <p style="text-align:justify"><strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">Methods: </span></span></strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">We conducted a retrospective, single-center study on all young individuals hospitalized with ACS between January 1, 2013, and October 30, 2023. For women and men, we defined being young as having 45 years or less. The median follow-up period was 4.5 years (SD 2.9). Demographics, clinical characteristics, and outcomes were analyzed, with MACE defined as the composite of total mortality, myocardial infarction, stroke, and hospitalization for heart failure.</span></span></p> <p style="text-align:justify"><strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">Results: </span></span></strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">Of the 130 patients who experienced ACS, 22.3% were women, with a mean age of 41.1 years (SD 3.9). In the women’s group, 93.1% had at least one cardiovascular risk factor: 65.5% were overweight or obese, 62.1% were smokers, 62.1% had dyslipidemia, 27.6% had hypertension, 6.9% had diabetes and 24.1% had a family history of premature ACS. Less frequent comorbidities included drug use (6.9%) and autoimmune diseases (6.9%). </span></span></p> <p style="text-align:justify"><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">Regarding clinical presentation, 69% of women were diagnosed with STEMI, 17.2% with NSTEMI, and 13.8% were admitted with unstable angina. Cardiorespiratory arrest occurred in 3.4% of cases. Upon admission, 41.4% had an ejection fraction (EF) below 50%. Most women had single-vessel disease (79.3%), predominantly affecting the left anterior descending artery (62.1%). Atherosclerosis was the leading cause of ACS (74.9%), followed by embolism (10.3%) and spontaneous coronary artery dissection (10.3%). Comparing men and women, the only statistically significant difference in demographic characteristics, risk factors, and clinical presentation was the proportion of smokers (62.1% in women vs. 84.2% in men, p=0.017). During follow-up, 17.2% of women developed MACE, with cardiovascular mortality at 5.4% and recurrent myocardial infarction at 6.9%. There were no significant differences between sexes regarding the prognosis of developing MACE.</span></span></p> <p style="text-align:justify"><strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">Conclusion: </span></span></strong><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif">Our study reveals that the clinical presentation and diagnosis of ACS in young women closely resemble that of men when baseline characteristics are similar. However, the prognosis is concerning, with a high incidence of MACE in both sexes. Early intervention targeting cardiovascular risk factors, particularly smoking, is essential, regardless of young age or female sex.</span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site