Login
Search
Search
0 Dates
2025
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
CPC 2025
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Left Atrial Strain as a Predictor of Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy
Session:
SESSÃO DE POSTERS 38 - ANÁLISE DE DEFORMAÇÃO MIOCÁRDICA
Speaker:
Inês Ferreira Neves
Congress:
CPC 2025
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
17. Myocardial Disease
Subtheme:
17.2 Myocardial Disease – Epidemiology, Prognosis, Outcome
Session Type:
Cartazes
FP Number:
---
Authors:
Inês Ferreira Neves; Mariana Caetano Coelho; André Ferreira; Pedro Garcia Brás; Isabel Cardoso; José Miguel Viegas; Inês Almeida; António Fiarresga; Pedro Silva Cunha; Rui Cruz Ferreira; Mário Martins Oliveira; Sílvia Aguiar Rosa
Abstract
<p>Introduction: Atrial fibrillation (AF) stands as the prevailing arrhythmia across all forms of cardiomyopathies. The occurrence of AF in individuals with hypertrophic cardiomyopathy (HCM) is 4 to 6 times more frequent compared to the general population of the same age. Patients (P) with HCM and FA are at higher risk of adverse outcomes.To date, there is not a widely validated model that can predict the risk for development of AF in P with HCM. We aimed to study the role of left atrial (LA) myocardial deformation imaging as a toll for predicting FA development, in a population with HCM.</p> <p><br /> Methods: P with HCM accompanied at our Cardiomyopathies Center who had no palpitations or documented AF at the time of echocardiographic evaluation were included. During follow-up, AF was established as an atrialtachyarrhythmia with uncoordinated atrial electrical activation lasting more than 30 seconds. For evaluation ofoutcomes, our cohort was divided into two groups (with and without AF). For the group with AF, the last transthoracic echocardiogram (TTE) performed before the diagnosis of AF was considered, for the group without AF, a TTE was analyzed in P with a similar follow-up duration. LA deformation imaging using two-dimensional speckle tracking echocardiography was performed according to the consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging.</p> <p><br /> Results: Forty-nine P with HCM (age 70.60±12.0, 43% male sex) were included. Twenty-six (53%; age 63.3±13.11,30.4% male sex) developed AF during the follow-up (FU) (mean FU of 29,5± 25 months). The groups had similar baseline clinical and demographic characteristics, and no significant differences were registered when comparing clinical aspects or regular medication. When analyzing the LA strain, there were no significative differences between the reservoir or conduit phases of the LA cycle, in either apical four chamber (A4C) view, apical two chamber (A2C) view or biplane analysis. The contraction phase of the LA cycle was significantly different between the two groups (p=0.02 for A4C, p=0.04 for A2C and p=0.05 for biplane). The ROC curves were drawn,with an area under the curve of 0.665 for A4C, 0.698 for A2C and 0.673 for biplane. Based on ROC curve analysis, an optimal cut-off point of -8.5% for sensitivity and specificity in the contraction phase of the LA cycle strain was determined. After Cox regression analysis, P with a value of LA strain for the contraction phase ≤-8.5% had a higher risk of developing AF (hazard ratio [HR] 4.29; 95% confidence interval [CI] 1.25-14.74, pvalue 0.021).</p> <p><br /> Conclusion: In our cohort of HCM P, atrial strain, particularly the contraction phase of the LA cycle, appears to be a valuable predictor for the development of AF.</p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site