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Atrial parameters generated by artificial intelligence in cardiac magnetic resonance and its association with atrial fibrillation in patients with hypertrophic cardiomyopathy
Session:
SESSÃO DE POSTERS 47 - AVALIAÇÃO CARDÍACA POR TC E/OU RM
Speaker:
Marta Paralta De Figueiredo
Congress:
CPC 2025
Topic:
B. Imaging
Theme:
03. Imaging
Subtheme:
03.3 Cardiac Magnetic Resonance
Session Type:
Cartazes
FP Number:
---
Authors:
Marta Paralta de Figueiredo; Rafael Viana; Antonio Almeida; Rita Louro; Mguel Carias; Diogo Brás; Bruno Piçarra; Manuel Trinca
Abstract
<p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Introduction: Atrial fibrillation (AF) is an important comorbidity in hypertrophic cardiomyopathy (HCM), increasing rates of stroke and mortality. Therefore, developing new non-invasive strategies for earlier diagnosis, such as using artificial intelligence (AI) generated parameters from cardiac magnetic resonance (CMR) can help improve outcomes in patients with HCM.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Purpose: Our study aimed to investigate if there was an association between AF and atrial AI-derived CMR parameters in individuals with HCM.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Methods: We retrospectively analyzed a population of patients submitted to CMR, selected those with hypertrophic cardiomyopathy (HCM) and divided them in two groups – those with and without AF. We documented demographic factors, left atrial ejection fraction (LAEF), right and left atrial volumes and the longitudinal LA shortening obtained through AI in CMR for both groups. We then performed univariate analysis to establish the relationship between variables and multivariate analysis to identify independent predictors.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Results: Out of 103 patients, 37,9% (n=39) had HCM. When comparing groups, 59% were male, with mean age of 61±13 years with no differences between groups. However, patients with AF had significantly lower LAEF (34,1% vs 50,9%, p=0,002), higher indexed diastolic LA volume (66,2mL vs 42,8mL, p= 0,003) and lower left atrial longitudinal shortening (11,8 vs 18,2, p=0,033). In multivariate analysis, nevertheless, none proved to be independently significant.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">Conclusion: CMR derived lower LAEF, higher indexed diastolic LA volume and lower left atrial longitudinal shortening are associated with AF in patients with HCM and could be an earlier indicator of development of arrhythmia and more complex cardiomyopathy. Although these were not independently associated, further studies with a larger population are required to establish possible predictors.</span></span></p>
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