Login
Search
Search
0 Dates
2025
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
CPC 2025
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Characterization of Patients with Left Main Coronary Artery Disease in Non-Acute Settings
Session:
SESSÃO DE POSTERS 40 - INTERVENÇÃO CORONÁRIA
Speaker:
Simão De Almeida Carvalho
Congress:
CPC 2025
Topic:
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
Theme:
12. Coronary Artery Disease (Chronic)
Subtheme:
12.6 Coronary Artery Disease - Clinical
Session Type:
Cartazes
FP Number:
---
Authors:
Simão De Almeida Carvalho; Tiago Aguiar; Carlos Costa; Adriana Pacheco; Inês Cruz; Gil Pires; Anabela Capela; Sónia Almeida; Andreia Fernandes; Tiago Adrega; Joana Ribeiro; Ana Briosa
Abstract
<p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000"><strong>Introduction:</strong></span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000"><span style="color:black">Left main coronary artery disease (LM-CAD) is linked to poor outcomes even in chronic settings, with revascularization improving prognosis regardless of symptoms or documented ischemia.</span></span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000"><span style="color:black">Updated European CCS guidelines redefined pre-test probability (PTP), increasing the 'very low probability' range.</span></span></span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000"><strong>Objective:</strong></span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000">To characterize the clinical profiles, diagnostic pathways, and management of patients with LM-CAD in </span></span>chronic the setting.</span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000"><strong>Methods:</strong></span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000">Retrospective cohort study of patients undergoing cardiac catheterization between May 2023 and November 2024.</span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000">Patients were included if they had LM stenosis ≥50% by angiography. Exclusion criteria were: acute presentations (positive troponin), Prior CABG or severe valvular disease. </span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000">Analyses were performed using SPSS.</span></span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000"><strong>Results:</strong></span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000">The study included 27 patients, 81.5% male, mean age of 68.9 ± 9.3 years. Patients had 2.4 ± 0.8 cardiovascular risk factors; dyslipidemia (85.2%) and hypertension (74.1%) were most common.</span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000">Regarding clinical presentation, <span style="color:black">Chest pain (66.7%) was most common clinical presentation, followed by dyspnea (14.8%), ventricular arrhythmias, and asymptomatic left ventricular dysfunction (18.5% each)</span>. Among those with chest pain, the median ESC symptom score was 3 (IQR: 2.5–3).</span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000">Using the Risk Factor-Weighted Clinical Likelihood model, the mean PTP was 26.3 ± 12.8%, corresponding to a moderate likelihood of obstructive CAD with 3 patients in the low and 1 in the very low-likelihood range. Notably, 70.4% of patients had at least one significant risk modifier. The most common were left ventricular dysfunction in 44.4% of cases, and baseline electrocardiographic abnormalities such as Q-waves or ST-segment changes in 37.0%.</span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000">Regarding diagnostic modalities, 29.6% of patients were refered directly to invasive evaluation and 14.8% after treadmill test. This reflects the presence of high-risk criteria in exercise stress tests, such as a Duke Treadmill Score < -10, the occurrence of new-onset or low-threshold angina, or a high pre-test probability (>85%) of coronary artery disease. Regarding non-invasive diagnostic methods, stress single-photon emission computed tomography (SPECT) was performed in 18.5% of patients, while coronary computed tomography angiography and stress echocardiography were each used in 14.8%. Among patients undergoing non-invasive tests, 78.9% had high-risk criteria.</span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000">Regarding revascularization, CABG was the predominant modality (59.2%) and percutaneous coronary intervention (PCI) was undertaken in 25.9% of cases. Two patients were managed conservatively due to significant comorbidities. During the short follow-up period, one death was recorded, involving a patient awaiting CABG.</span></span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000"><strong>Conclusion:</strong></span></span></span></p> <p style="text-align:justify"><span style="font-size:16px"><span style="font-family:Arial,Helvetica,sans-serif"><span style="color:#000000">This study characterizes non-acute LM-CAD patients under revised ESC CCS guidelines. Most had moderate PTP, but high-risk modifiers highlight the need for personalized risk assessment.</span></span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site