Login
Search
Search
0 Dates
2025
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
CPC 2025
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Impact of Cardiovascular Risk Factors in Myocardial Work
Session:
SESSÃO DE POSTERS 38 - ANÁLISE DE DEFORMAÇÃO MIOCÁRDICA
Speaker:
Luís Miguel Cardoso Cotrim
Congress:
CPC 2025
Topic:
B. Imaging
Theme:
03. Imaging
Subtheme:
03.1 Echocardiography
Session Type:
Cartazes
FP Number:
---
Authors:
Luís Cotrim; Rita Santos; António Carvahho; Lígia Mendes
Abstract
<p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif"><strong>Background</strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif">Myocardial work (MW) is an emerging echocardiographic tool that quantifies left ventricular function through pressure–strain loops. Validated against invasive pressure–volume measurements, MW provides a comprehensive assessment of myocardial performance. In this study, we evaluated the prevalence and severity of subclinical left ventricular dysfunction in a general population and examined its association with cardiovascular (CV) risk factors.</span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif"><strong>Methods</strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif">We conducted a retrospective, single-center analysis of patients with no known cardiovascular disease, who underwent MW assessment between January 2022 and November 2024. Participants were characterized based on traditional CV risk factors, and MW parameters were analyzed, including global constructive work (GCW), global wasted work (GWW), global work index (GWI), and global work efficiency (GWE).</span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif"><strong>Results</strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif">A total of 822 patients were included (52.8% male, mean age 63 ± 11 years, BMI 27.5 ± 3.8 kg/m²). Among them, 21% were obese, 14% had diabetes, 65% had hypercholesterolemia, and 39% were smokers or recent quitters. Only 15% had no CV risk factors. Basal clinical and echocardiographic parameters were withing the normal range: SBP 124±16mmHg, DBP 74±10, LVEF 59.7±7, E/e’ 7.3±2.5, PASP 23±6mmHg, GWE 91.7±4.4%, GWI 1551±305mmHg%, GCW 1903±343mmHg% and GWW 165±95mmHg%. </span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif">Univariable analysis revealed that GWW and GWE were significantly associated with sex, age, obesity, hypercholesterolemia, and smoking (Table 1). Multivariable analysis identified obesity and hypercholesterolemia as independent predictors of GWW and GWE, explaining 8% of the variance (partial η² = 0.08). After adjusting for age and sex, obesity remained the sole independent determinant of GWW and GWE. Obese patients had higher GWW (189 ± 109 vs. 159 ± 91 mmHg%, p = 0.028) and lower GWE (90.7 ± 4.9 vs. 92.0 ± 4.3%, p = 0.007).</span></span></p> <p style="text-align:justify"> </p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif"><strong>Conclusion</strong></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif">This study highlights that obesity is a key, independent contributor to impaired myocardial efficiency, reflected by higher GWW and lower GWE. These findings underscore the importance of targeting obesity as a modifiable risk factor to mitigate early left ventricular dysfunction and improve cardiovascular outcomes.</span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site