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Gender Differences in Atrial Fibrillation Patients Undergoing Catheter Ablation
Session:
SESSÃO DE POSTERS 53 - FIBRILHAÇÃO AURICULAR E ARRITMIAS AURICULARES COMPLEXAS
Speaker:
Sofia Nogueira Fernandes
Congress:
CPC 2025
Topic:
C. Arrhythmias and Device Therapy
Theme:
05. Atrial Fibrillation
Subtheme:
05.4 Atrial Fibrillation - Treatment
Session Type:
Cartazes
FP Number:
---
Authors:
Sofia Nogueira Fernandes; Sofia Lobato Afonso; Mónica Dias; Filipe Vilela; Carla Ferreira; Inês Conde; Jorge Marques; Vítor Hugo Pereira; Sérgia Rocha
Abstract
<p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif"><strong><span style="font-size:11.0pt">Background:</span></strong><span style="font-size:11.0pt"> Previous studies evaluating s</span><span style="font-size:11.0pt">ex-specific outcomes </span><span style="font-size:11.0pt">in patients undergoing catheter ablations for atrial fibrillation (AF) are controversial. Delays in diagnosis, clinic visits, and ablation can impact patient outcomes. This study aimed to compare the time intervals between key stages in the management of AF — diagnosis, clinic visit, catheter ablation, and initiation of antiarrhythmic drugs (AAD) — between men and women.</span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif"><strong><span style="font-size:11.0pt">Methods:</span></strong><span style="font-size:11.0pt"> We retrospectively analysed data from 132 patients who underwent catheter ablation for AF, between January 2018 and December 2021. Clinical characteristics, procedural details, time intervals between key stages in the management, and outcomes were compared between genders. </span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif"><strong><span style="font-size:11.0pt">Results:</span></strong><span style="font-size:11.0pt"> Patients undergoing AF ablation were mainly men (66%). Mean age was 58.6+9.5 years. Women were more likely to present with paroxysmal AF (75.6% vs. 55.2%, p = 0.022). Men showed higher rates of congestive heart failure (12.6% vs. 2.2%, p = 0.048). No significant differences were observed in CHA2DS2-VA scores and antiarrhythmic drug use. At 12 months, although women had more </span><span style="font-size:11.0pt">arrhythmia recurrence, </span><span style="font-size:11.0pt">the difference was not statistically significant (28.9% women vs. 18.4% men, p = 0.167).</span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif"><span style="font-size:11.0pt">Women tend to have a longer time between the initial AF diagnosis and their first cardiology clinic visit, with a median of 325 days compared to 146 days for men (p=0.028), suggesting that gender may influence the time to access specialized care. Although women have a longer time from initial AF diagnosis to catheter ablation (median 1558 days vs 1250 days), the difference is not statistically significant (p=0.148). The time from the first cardiology clinic visit to catheter ablation is similar between men and women, suggesting that once cardiology care begins, referral times for ablation do not differ substantially between genders.</span></span></span></p> <p style="text-align:justify"><span style="font-size:12pt"><span style="font-family:Aptos,sans-serif"><strong><span style="font-size:11.0pt">Conclusions:</span></strong><span style="font-size:11.0pt"> In this cohort study of patients, women experience a greater delay in accessing cardiology care after an AF diagnosis. This may reflect differences in clinical presentation between genders or barriers to access. Timely specialized care could be a critical point for interventions aimed at promoting the best clinical outcomes in AF management, insuring equity between genders. Further research is needed to better understand the implications of these differences on treatment outcomes.</span></span></span></p>
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