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Vascular Complications after MANTA Vascular Closure Device following Transcatheter Aortic Valve Implantation
Session:
SESSÃO DE POSTERS 05 - TAVI 1
Speaker:
Tomás M. Carlos
Congress:
CPC 2025
Topic:
H. Interventional Cardiology and Cardiovascular Surgery
Theme:
25. Interventional Cardiology
Subtheme:
25.3 Non-coronary Cardiac Intervention
Session Type:
Cartazes
FP Number:
---
Authors:
Tomás M. Carlos; Mafalda Griné; Diogo Fernandes; Joana Guimarães; Gonçalo Terleira Batista; Tatiana Santos; Bernardo Resende; Luísa Gomes Rocha; Luís Leite; Marco Costa; Lino Gonçalves
Abstract
<p><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Introduction:</strong></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif">Vascular complications are common and serious adverse events following transcatheter aortic valve implantation (TAVI), with incidence ranging from 5% to 20%. Recent advances, such as the MANTA vascular closure device (MANTA-VCD), aim to reduce these complications. This study aimed to evaluate vascular complications associated with main arterial access after TAVI, focusing on the performance of the MANTA-VCD system.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Methods:</strong></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif">We conducted a retrospective, single-centre study of patients who underwent TAVI between March 2020 and September 2023. Patients who did not use the MANTA-CVD system for main arterial access closure were excluded. Baseline characteristics were assessed, and the primary outcome was the incidence of vascular complications. Potential predictors were analysed using binary logistic regression.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Results:</strong></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif">In our cohort of 628 patients, 604 (96.1%) used the MANTA-VCD system for arterial access closure. The mean age was 81.6 ± 6.0 years, with a balanced gender distribution. Cardiovascular risk factors were common, with 83.4% having arterial hypertension and 70.7% dyslipidaemia. The right common femoral artery was the most used access site (71.9%). Vascular complications occurred in 35 patients (5.8%), with local hematomas or bleeding requiring transfusion as the most common events. Among these, 65.7% were female, 88.6% had arterial hypertension, and 80.0% had dyslipidaemia. The right common femoral artery was the most frequently affected site (60%), although left common femoral artery showed statistically significant higher prevalence of complications (<em>p</em>=0.001). Dialysis patients also had a notable prevalence among those with complications (5.7%). Binary logistic regression identified female gender (OR 2.49; CI 1.18-5.29; <em>p</em>=0.017), dialytic treatment (OR 9.74; CI 1.56-60.83, <em>p</em>=0.015) and left common femoral artery access (OR 5.47, CI 1.69-17.7, <em>p</em>=0.005) as potential predictors of vascular complications.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Conclusion:</strong></span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif">The use of the MANTA-CVD system for main arterial access closure in TAVI was associated with a low rate of vascular complications (5.8%), aligning with previously reported outcomes and supporting its safety and efficacy. Female gender, dialysis and less commonly used primary access sites emerged as predictors of vascular complications, highlighting the importance of targeted evaluation in these subgroups.</span></span></p>
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